Cluster of factors related to metabolic changes in older individuals: a cross-sectional study

ABSTRACT BACKGROUND: Exposure to multiple risk factors related to metabolic changes can negatively affect the health status of older individuals. OBJECTIVE: To investigate the clustering of factors related to metabolic changes in older individuals. DESIGN AND SETTING: This was a cross-sectional s...

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Main Authors: Clarice Alves dos Santos, Mariana Alves dos Santos, Manuela Alves dos Santos, Milena Fernandez Dias, Lélia Renata Carneiro Vasconcelos, Saulo Vasconcelos Rocha
Format: Article
Language:English
Published: Associação Paulista de Medicina 2025-04-01
Series:São Paulo Medical Journal
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802025000200208&lng=en&tlng=en
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author Clarice Alves dos Santos
Mariana Alves dos Santos
Manuela Alves dos Santos
Milena Fernandez Dias
Lélia Renata Carneiro Vasconcelos
Saulo Vasconcelos Rocha
author_facet Clarice Alves dos Santos
Mariana Alves dos Santos
Manuela Alves dos Santos
Milena Fernandez Dias
Lélia Renata Carneiro Vasconcelos
Saulo Vasconcelos Rocha
author_sort Clarice Alves dos Santos
collection DOAJ
description ABSTRACT BACKGROUND: Exposure to multiple risk factors related to metabolic changes can negatively affect the health status of older individuals. OBJECTIVE: To investigate the clustering of factors related to metabolic changes in older individuals. DESIGN AND SETTING: This was a cross-sectional study involving 287 older individuals (≥ 60 years old) enrolled in the Family Health Strategy in the municipality of Ibicuí, state of Bahia. METHODS: Factors associated with metabolic changes were abdominal obesity, self-reported diabetes, high blood pressure, sedentary behavior, and physical inactivity. Clustering was defined by an observed-to-expected prevalence (O/E) ratio greater than 1.20. The association between these factors was analyzed using multiple logistic regression. RESULTS: A total of seven clusters were identified with a predominance of diabetes, hypertension, sedentary behavior, and abdominal obesity (O/E = 2.28). Older adults were more likely to present with physical inactivity, diabetes, blood pressure, and sedentary behavior simultaneously (Odds Ratio [OR] = 7.78; 95% confidence interval [CI] = 1.25–48.42). Negative health perception was associated with the combination of high blood pressure, sedentary behavior, and abdominal obesity (OR = 0.23; 95%CI = 0.25–0.92); female sex with the cluster of physical inactivity and abdominal obesity (OR = 0.12; 95%CI = 0.04–0.35); and the occurrence of physical inactivity without the presence of other factors (OR = 3.87; 95%CI = 1.66–8.99). CONCLUSIONS: The combination of risk factors related to metabolic changes represents a greater probability of health problems than individual factors. Therefore, investigating the association between these factors will help in planning targeted interventions.
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spelling doaj-art-3fca990737d34ac6be8fd2f0d421fe9f2025-08-20T03:11:30ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-94602025-04-01143210.1590/1516.3180.2023.0283.r1.30082024Cluster of factors related to metabolic changes in older individuals: a cross-sectional studyClarice Alves dos Santoshttps://orcid.org/0000-0002-2730-5117Mariana Alves dos Santoshttps://orcid.org/0000-0001-8695-6449Manuela Alves dos Santoshttps://orcid.org/0000-0001-8643-0279Milena Fernandez Diashttps://orcid.org/0000-0002-8559-2847Lélia Renata Carneiro Vasconceloshttps://orcid.org/0000-0003-1209-4799Saulo Vasconcelos Rochahttps://orcid.org/0000-0001-8655-5151ABSTRACT BACKGROUND: Exposure to multiple risk factors related to metabolic changes can negatively affect the health status of older individuals. OBJECTIVE: To investigate the clustering of factors related to metabolic changes in older individuals. DESIGN AND SETTING: This was a cross-sectional study involving 287 older individuals (≥ 60 years old) enrolled in the Family Health Strategy in the municipality of Ibicuí, state of Bahia. METHODS: Factors associated with metabolic changes were abdominal obesity, self-reported diabetes, high blood pressure, sedentary behavior, and physical inactivity. Clustering was defined by an observed-to-expected prevalence (O/E) ratio greater than 1.20. The association between these factors was analyzed using multiple logistic regression. RESULTS: A total of seven clusters were identified with a predominance of diabetes, hypertension, sedentary behavior, and abdominal obesity (O/E = 2.28). Older adults were more likely to present with physical inactivity, diabetes, blood pressure, and sedentary behavior simultaneously (Odds Ratio [OR] = 7.78; 95% confidence interval [CI] = 1.25–48.42). Negative health perception was associated with the combination of high blood pressure, sedentary behavior, and abdominal obesity (OR = 0.23; 95%CI = 0.25–0.92); female sex with the cluster of physical inactivity and abdominal obesity (OR = 0.12; 95%CI = 0.04–0.35); and the occurrence of physical inactivity without the presence of other factors (OR = 3.87; 95%CI = 1.66–8.99). CONCLUSIONS: The combination of risk factors related to metabolic changes represents a greater probability of health problems than individual factors. Therefore, investigating the association between these factors will help in planning targeted interventions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802025000200208&lng=en&tlng=enRisk factorsMetabolic syndromePublic healthElderlyElderly healthCross-sectional studiesMetabolic changes
spellingShingle Clarice Alves dos Santos
Mariana Alves dos Santos
Manuela Alves dos Santos
Milena Fernandez Dias
Lélia Renata Carneiro Vasconcelos
Saulo Vasconcelos Rocha
Cluster of factors related to metabolic changes in older individuals: a cross-sectional study
São Paulo Medical Journal
Risk factors
Metabolic syndrome
Public health
Elderly
Elderly health
Cross-sectional studies
Metabolic changes
title Cluster of factors related to metabolic changes in older individuals: a cross-sectional study
title_full Cluster of factors related to metabolic changes in older individuals: a cross-sectional study
title_fullStr Cluster of factors related to metabolic changes in older individuals: a cross-sectional study
title_full_unstemmed Cluster of factors related to metabolic changes in older individuals: a cross-sectional study
title_short Cluster of factors related to metabolic changes in older individuals: a cross-sectional study
title_sort cluster of factors related to metabolic changes in older individuals a cross sectional study
topic Risk factors
Metabolic syndrome
Public health
Elderly
Elderly health
Cross-sectional studies
Metabolic changes
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802025000200208&lng=en&tlng=en
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