Predictors of medication use during pregnancy: a cohort study.
Background Sociodemographic characteristics and health behaviours are associated with medication use in pregnancy, but it is unclear if they are independent predictors because women´s health status has hardly been accounted for. We aimed to identify predictors of use of medications and of iron/foli...
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| Format: | Article |
| Language: | English |
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Milano University Press
2018-06-01
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| Series: | Epidemiology, Biostatistics and Public Health |
| Online Access: | https://ebph.it/article/view/12926 |
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| author | Federica Pisa Federico Romanese Francesca Palese Fabio Barbone |
| author_facet | Federica Pisa Federico Romanese Francesca Palese Fabio Barbone |
| author_sort | Federica Pisa |
| collection | DOAJ |
| description | Background
Sociodemographic characteristics and health behaviours are associated with medication use in pregnancy, but it is unclear if they are independent predictors because women´s health status has hardly been accounted for. We aimed to identify predictors of use of medications and of iron/folic acid.
Methods
This cohort included pregnant women recruited in a prenatal clinic in Trieste, Italy, from 2007 to 2009. Dispensations were obtained from the regional outpatient dispensation database through record linkage. We calculated the Odds Ratio (OR), with 95% confidence interval (95%CI), of ≥ 1 dispensation of (a) any medication and (b) iron/folic acid, using unconditional logistic regression. The final model adjusted for age, partner education, housing size, comorbidities.
Findings
Of 767 women, 70.5% had ≥ 1 dispensation of any medication and 46.1% of iron/folic acid. Use of any medication was predicted by immigrant status of the woman (OR 1.21; 95%CI 0.57–2.53) or of her partner (1.51; 0.67–3.40), ≤ high school degree of the woman (1.11; 0.61–2.03) or of her partner (1.21; 0.75–1.95), unemployment (1.47; 0.72–2.98), smoking (1.25; 0.65–2.40), alcohol consumption (≥5 drinks/week: 2.78; 1.78–4.34), and obesity (1.33; 0.59–2.99). Use of iron and/or folic acid was predicted by ≤ high school degree (0.65; 0.40–1.08), smoking (0.80: 0.47–1.37), and obesity (0.62; 0.31–1.25).
Discussion
In this cohort, characteristics including education, immigrant and employment status, smoking, alcohol consumption, and obesity independently predicted medication use. Interventions to promote safe use of medications should carefully consider women´s characteristics. |
| format | Article |
| id | doaj-art-3fc39d558f784bebb990f7734b5ea91c |
| institution | DOAJ |
| issn | 2282-0930 |
| language | English |
| publishDate | 2018-06-01 |
| publisher | Milano University Press |
| record_format | Article |
| series | Epidemiology, Biostatistics and Public Health |
| spelling | doaj-art-3fc39d558f784bebb990f7734b5ea91c2025-08-20T03:10:03ZengMilano University PressEpidemiology, Biostatistics and Public Health2282-09302018-06-0115210.2427/1292611167Predictors of medication use during pregnancy: a cohort study.Federica Pisa0Federico Romanese1Francesca Palese2Fabio Barbone31. Leibniz Institute for Prevention Research and Epidemiology - BIPS GmbH Department Clinical Epidemiology Unit Drug Safety Germany 2. Institute of Hygiene and Clinical Epidemiology, University Hospital of Udine, Udine, ItalyDepartment of Medicine, University of Udine, Udine, ItalyDepartment of Medicine, University of Udine, Udine, Italy1. Institute for Maternal and Child Health - IRCCS “Burlo Garofolo”, Trieste, Italy. 2. Department of Medicine, University of Udine, Udine, ItalyBackground Sociodemographic characteristics and health behaviours are associated with medication use in pregnancy, but it is unclear if they are independent predictors because women´s health status has hardly been accounted for. We aimed to identify predictors of use of medications and of iron/folic acid. Methods This cohort included pregnant women recruited in a prenatal clinic in Trieste, Italy, from 2007 to 2009. Dispensations were obtained from the regional outpatient dispensation database through record linkage. We calculated the Odds Ratio (OR), with 95% confidence interval (95%CI), of ≥ 1 dispensation of (a) any medication and (b) iron/folic acid, using unconditional logistic regression. The final model adjusted for age, partner education, housing size, comorbidities. Findings Of 767 women, 70.5% had ≥ 1 dispensation of any medication and 46.1% of iron/folic acid. Use of any medication was predicted by immigrant status of the woman (OR 1.21; 95%CI 0.57–2.53) or of her partner (1.51; 0.67–3.40), ≤ high school degree of the woman (1.11; 0.61–2.03) or of her partner (1.21; 0.75–1.95), unemployment (1.47; 0.72–2.98), smoking (1.25; 0.65–2.40), alcohol consumption (≥5 drinks/week: 2.78; 1.78–4.34), and obesity (1.33; 0.59–2.99). Use of iron and/or folic acid was predicted by ≤ high school degree (0.65; 0.40–1.08), smoking (0.80: 0.47–1.37), and obesity (0.62; 0.31–1.25). Discussion In this cohort, characteristics including education, immigrant and employment status, smoking, alcohol consumption, and obesity independently predicted medication use. Interventions to promote safe use of medications should carefully consider women´s characteristics.https://ebph.it/article/view/12926 |
| spellingShingle | Federica Pisa Federico Romanese Francesca Palese Fabio Barbone Predictors of medication use during pregnancy: a cohort study. Epidemiology, Biostatistics and Public Health |
| title | Predictors of medication use during pregnancy: a cohort study. |
| title_full | Predictors of medication use during pregnancy: a cohort study. |
| title_fullStr | Predictors of medication use during pregnancy: a cohort study. |
| title_full_unstemmed | Predictors of medication use during pregnancy: a cohort study. |
| title_short | Predictors of medication use during pregnancy: a cohort study. |
| title_sort | predictors of medication use during pregnancy a cohort study |
| url | https://ebph.it/article/view/12926 |
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