Global Burden of Endometriosis in 204 Countries and Territories from 1990 to 2019

Background: To our knowledge, no systematic update on the descriptive epidemiology of endometriosis and its trends has been published based on the Global Burden of Disease (GBD) datasets. To investigate the burden of endometriosis in 204 countries and territories from 1990 to 2019. Methods: Data wer...

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Main Authors: Jinhui Feng, Shitong Zhang, Jiadong Chen, Jue Zhu, Jie Yang
Format: Article
Language:English
Published: IMR Press 2022-10-01
Series:Clinical and Experimental Obstetrics & Gynecology
Subjects:
Online Access:https://www.imrpress.com/journal/CEOG/49/10/10.31083/j.ceog4910235
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author Jinhui Feng
Shitong Zhang
Jiadong Chen
Jue Zhu
Jie Yang
author_facet Jinhui Feng
Shitong Zhang
Jiadong Chen
Jue Zhu
Jie Yang
author_sort Jinhui Feng
collection DOAJ
description Background: To our knowledge, no systematic update on the descriptive epidemiology of endometriosis and its trends has been published based on the Global Burden of Disease (GBD) datasets. To investigate the burden of endometriosis in 204 countries and territories from 1990 to 2019. Methods: Data were extracted from the Global Burden of Disease (GBD) 2019 datasets. Estimated annual percentage changes (EAPCs) were calculated to assess trends in the incidence and disability-adjusted life-years (DALYs) of endometriosis. Measures were stratified by region, country, age, and socio-demographic index (SDI). Results: From 1990 to 2019, the global incidence and DALYs of endometriosis increased by 10.37% and 16.36%, respectively. However, both the age-standardized incidence rate (ASIR) and age-standardized DALY rate of endometriosis showed downward trends (EAPC = –0.81 and –0.80, respectively). The ASIR decreased in all SDI regions, with the largest decrease observed in low-middle SDI regions [EAPC = –1.19, 95% Confidence Interval (CI): –1.21 to –1.16] except Eastern Europe, the only region where the ASIR increased (EAPC = 0.15, 95% CI: 0.01 to 0.29). The largest decreases in the ASIR and age-standardized DALY rate of endometriosis were observed in Qatar and Oman, respectively. Conclusions: The global incidence and DALYs of endometriosis continued to increase during 1990–2019. However, the ASIR and age-standardized DALY rate have shown decreasing trends worldwide, with increasing trends detected only in Eastern Europe.
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spelling doaj-art-3fbe79cf79244514a9720f2d42761ffb2025-08-20T01:56:20ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632022-10-01491023510.31083/j.ceog4910235S0390-6663(22)01941-8Global Burden of Endometriosis in 204 Countries and Territories from 1990 to 2019Jinhui Feng0Shitong Zhang1Jiadong Chen2Jue Zhu3Jie Yang4The Third Department of Gynecology, Ningbo Women & Children's Hospital, 315012 Ningbo, Zhejiang, ChinaThe Third Department of Gynecology, Ningbo Women & Children's Hospital, 315012 Ningbo, Zhejiang, ChinaThe Third Department of Gynecology, Ningbo Women & Children's Hospital, 315012 Ningbo, Zhejiang, ChinaThe Third Department of Gynecology, Ningbo Women & Children's Hospital, 315012 Ningbo, Zhejiang, ChinaThe Third Department of Gynecology, Ningbo Women & Children's Hospital, 315012 Ningbo, Zhejiang, ChinaBackground: To our knowledge, no systematic update on the descriptive epidemiology of endometriosis and its trends has been published based on the Global Burden of Disease (GBD) datasets. To investigate the burden of endometriosis in 204 countries and territories from 1990 to 2019. Methods: Data were extracted from the Global Burden of Disease (GBD) 2019 datasets. Estimated annual percentage changes (EAPCs) were calculated to assess trends in the incidence and disability-adjusted life-years (DALYs) of endometriosis. Measures were stratified by region, country, age, and socio-demographic index (SDI). Results: From 1990 to 2019, the global incidence and DALYs of endometriosis increased by 10.37% and 16.36%, respectively. However, both the age-standardized incidence rate (ASIR) and age-standardized DALY rate of endometriosis showed downward trends (EAPC = –0.81 and –0.80, respectively). The ASIR decreased in all SDI regions, with the largest decrease observed in low-middle SDI regions [EAPC = –1.19, 95% Confidence Interval (CI): –1.21 to –1.16] except Eastern Europe, the only region where the ASIR increased (EAPC = 0.15, 95% CI: 0.01 to 0.29). The largest decreases in the ASIR and age-standardized DALY rate of endometriosis were observed in Qatar and Oman, respectively. Conclusions: The global incidence and DALYs of endometriosis continued to increase during 1990–2019. However, the ASIR and age-standardized DALY rate have shown decreasing trends worldwide, with increasing trends detected only in Eastern Europe.https://www.imrpress.com/journal/CEOG/49/10/10.31083/j.ceog4910235endometriosisincidencedisability-adjusted life-year (daly)global burden of disease
spellingShingle Jinhui Feng
Shitong Zhang
Jiadong Chen
Jue Zhu
Jie Yang
Global Burden of Endometriosis in 204 Countries and Territories from 1990 to 2019
Clinical and Experimental Obstetrics & Gynecology
endometriosis
incidence
disability-adjusted life-year (daly)
global burden of disease
title Global Burden of Endometriosis in 204 Countries and Territories from 1990 to 2019
title_full Global Burden of Endometriosis in 204 Countries and Territories from 1990 to 2019
title_fullStr Global Burden of Endometriosis in 204 Countries and Territories from 1990 to 2019
title_full_unstemmed Global Burden of Endometriosis in 204 Countries and Territories from 1990 to 2019
title_short Global Burden of Endometriosis in 204 Countries and Territories from 1990 to 2019
title_sort global burden of endometriosis in 204 countries and territories from 1990 to 2019
topic endometriosis
incidence
disability-adjusted life-year (daly)
global burden of disease
url https://www.imrpress.com/journal/CEOG/49/10/10.31083/j.ceog4910235
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AT shitongzhang globalburdenofendometriosisin204countriesandterritoriesfrom1990to2019
AT jiadongchen globalburdenofendometriosisin204countriesandterritoriesfrom1990to2019
AT juezhu globalburdenofendometriosisin204countriesandterritoriesfrom1990to2019
AT jieyang globalburdenofendometriosisin204countriesandterritoriesfrom1990to2019