Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabrics

Dibenzobarallene was used as a key intermediate for the synthesis of 2-(3-hydroxy-2-naphthoyl)-3,4,4a,5,10,10a-hexahydro-1H-5,10-benzenobenzo[g]phthalazine-1,4-dione (2). The previous compound was coupled with the appropriate diazonium chloride to give the corresponding 4-arylazo-2-naphthol derivati...

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Main Authors: Abd El-Galil M. Khalil, Moged A. Berghot, Moustafa A. Gouda
Format: Article
Language:English
Published: Springer 2016-03-01
Series:Journal of Saudi Chemical Society
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Online Access:http://www.sciencedirect.com/science/article/pii/S131961031200083X
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author Abd El-Galil M. Khalil
Moged A. Berghot
Moustafa A. Gouda
author_facet Abd El-Galil M. Khalil
Moged A. Berghot
Moustafa A. Gouda
author_sort Abd El-Galil M. Khalil
collection DOAJ
description Dibenzobarallene was used as a key intermediate for the synthesis of 2-(3-hydroxy-2-naphthoyl)-3,4,4a,5,10,10a-hexahydro-1H-5,10-benzenobenzo[g]phthalazine-1,4-dione (2). The previous compound was coupled with the appropriate diazonium chloride to give the corresponding 4-arylazo-2-naphthol derivatives 3a–l. Also, nitration, nitrosation and bromination of compound 2 afforded the corresponding nitro, nitroso and bromo derivatives 4–6, respectively. The synthesized compounds were established and evaluated as antibacterial agents. The results showed clearly that compounds 2, 3a, 3c, 3d, 3g, 3i, 4, 5 and 6 exhibited interesting high activities compared with reference drugs. Also, these compounds were applied to polyester as disperse dyes in which their color measurement and fastness properties were evaluated.
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institution Kabale University
issn 1319-6103
language English
publishDate 2016-03-01
publisher Springer
record_format Article
series Journal of Saudi Chemical Society
spelling doaj-art-3fb08bcccda645b6af5213157cf90fd92025-08-20T03:52:25ZengSpringerJournal of Saudi Chemical Society1319-61032016-03-0120216517210.1016/j.jscs.2012.06.007Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabricsAbd El-Galil M. KhalilMoged A. BerghotMoustafa A. GoudaDibenzobarallene was used as a key intermediate for the synthesis of 2-(3-hydroxy-2-naphthoyl)-3,4,4a,5,10,10a-hexahydro-1H-5,10-benzenobenzo[g]phthalazine-1,4-dione (2). The previous compound was coupled with the appropriate diazonium chloride to give the corresponding 4-arylazo-2-naphthol derivatives 3a–l. Also, nitration, nitrosation and bromination of compound 2 afforded the corresponding nitro, nitroso and bromo derivatives 4–6, respectively. The synthesized compounds were established and evaluated as antibacterial agents. The results showed clearly that compounds 2, 3a, 3c, 3d, 3g, 3i, 4, 5 and 6 exhibited interesting high activities compared with reference drugs. Also, these compounds were applied to polyester as disperse dyes in which their color measurement and fastness properties were evaluated.http://www.sciencedirect.com/science/article/pii/S131961031200083XNaphthoic acid hydrazideNaphthol dyesPolyester fabricsAntibacterialColor measurementsFastness properties
spellingShingle Abd El-Galil M. Khalil
Moged A. Berghot
Moustafa A. Gouda
Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabrics
Journal of Saudi Chemical Society
Naphthoic acid hydrazide
Naphthol dyes
Polyester fabrics
Antibacterial
Color measurements
Fastness properties
title Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabrics
title_full Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabrics
title_fullStr Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabrics
title_full_unstemmed Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabrics
title_short Synthesis and antibacterial activity of some new 3-hydroxy-2-naphthoic acid hydrazide derivatives for dyeing polyester fabrics
title_sort synthesis and antibacterial activity of some new 3 hydroxy 2 naphthoic acid hydrazide derivatives for dyeing polyester fabrics
topic Naphthoic acid hydrazide
Naphthol dyes
Polyester fabrics
Antibacterial
Color measurements
Fastness properties
url http://www.sciencedirect.com/science/article/pii/S131961031200083X
work_keys_str_mv AT abdelgalilmkhalil synthesisandantibacterialactivityofsomenew3hydroxy2naphthoicacidhydrazidederivativesfordyeingpolyesterfabrics
AT mogedaberghot synthesisandantibacterialactivityofsomenew3hydroxy2naphthoicacidhydrazidederivativesfordyeingpolyesterfabrics
AT moustafaagouda synthesisandantibacterialactivityofsomenew3hydroxy2naphthoicacidhydrazidederivativesfordyeingpolyesterfabrics