Integrins and pulmonary fibrosis: Pathogenic roles and therapeutic opportunities

Integrins and pulmonary fibrosis: Pathogenic roles and therapeutic opportunities

Characterized by the formation of fibrotic scars, pulmonary fibrosis (PF) involves a complex pathogenesis, limited treatment options, and a high mortality rate. Integrins—heterodimeric transmembrane proteins composed of α and β subunits—mediate extracellular matrix remodeling and regulate the physi...

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Bibliographic Details
Main Authors: Zhangyang Bi, Guodong Zang, Xiaodong Wang, Li Tian, Wei Zhang
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2025-06-01
Series:Biomolecules & Biomedicine
Subjects:
integrin
pulmonary fibrosis
PF
targeted therapy
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/12545
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