Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis
ABSTRACT Acute necrotizing otitis media is a severe middle ear infection which causes necrosis of the tympanic cavity. A 54‐year‐old female was presented who suffered from diabetes mellitus and end‐stage renal disease presenting with severe otalgia, initially thought to be necrotizing otitis externa...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
|
| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.70101 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832589899054710784 |
|---|---|
| author | Ermia Mousavi Mohammadi Mohsen Rajati Hossein Zarrinfar |
| author_facet | Ermia Mousavi Mohammadi Mohsen Rajati Hossein Zarrinfar |
| author_sort | Ermia Mousavi Mohammadi |
| collection | DOAJ |
| description | ABSTRACT Acute necrotizing otitis media is a severe middle ear infection which causes necrosis of the tympanic cavity. A 54‐year‐old female was presented who suffered from diabetes mellitus and end‐stage renal disease presenting with severe otalgia, initially thought to be necrotizing otitis externa. She rapidly progressed to total necrosis of the tympanic membrane. Further assessments confirmed a fungal disease caused by Candida tropicalis and Aspergillus flavus. Immediate antifungal therapy with amphotericin B and subsequent radical mastoidectomy managed to control the disease with no sign of necrosis after 3 months. Early diagnosis, aggressive systemic antifungal treatment, and surgical debridement are vital components for successful management of such cases. |
| format | Article |
| id | doaj-art-3fa419f1696f4134a0dbb8dd87e58fe9 |
| institution | Kabale University |
| issn | 2050-0904 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-3fa419f1696f4134a0dbb8dd87e58fe92025-01-24T05:08:46ZengWileyClinical Case Reports2050-09042025-01-01131n/an/a10.1002/ccr3.70101Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and MastoiditisErmia Mousavi Mohammadi0Mohsen Rajati1Hossein Zarrinfar2Department of Otorhinolaryngology, Sinus and Surgical Endoscopic Research Center, School of Medicine Mashhad University of Medical Sciences Mashhad IranDepartment of Otorhinolaryngology, Sinus and Surgical Endoscopic Research Center, School of Medicine Mashhad University of Medical Sciences Mashhad IranAllergy Research Center Mashhad University of Medical Sciences Mashhad IranABSTRACT Acute necrotizing otitis media is a severe middle ear infection which causes necrosis of the tympanic cavity. A 54‐year‐old female was presented who suffered from diabetes mellitus and end‐stage renal disease presenting with severe otalgia, initially thought to be necrotizing otitis externa. She rapidly progressed to total necrosis of the tympanic membrane. Further assessments confirmed a fungal disease caused by Candida tropicalis and Aspergillus flavus. Immediate antifungal therapy with amphotericin B and subsequent radical mastoidectomy managed to control the disease with no sign of necrosis after 3 months. Early diagnosis, aggressive systemic antifungal treatment, and surgical debridement are vital components for successful management of such cases.https://doi.org/10.1002/ccr3.70101AspergillusCandidafungalnecrotizingotitis media |
| spellingShingle | Ermia Mousavi Mohammadi Mohsen Rajati Hossein Zarrinfar Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis Clinical Case Reports Aspergillus Candida fungal necrotizing otitis media |
| title | Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis |
| title_full | Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis |
| title_fullStr | Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis |
| title_full_unstemmed | Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis |
| title_short | Unusual Presentation of a Rare Disease: A Case Report of Fungal Necrotizing Otitis Media and Mastoiditis |
| title_sort | unusual presentation of a rare disease a case report of fungal necrotizing otitis media and mastoiditis |
| topic | Aspergillus Candida fungal necrotizing otitis media |
| url | https://doi.org/10.1002/ccr3.70101 |
| work_keys_str_mv | AT ermiamousavimohammadi unusualpresentationofararediseaseacasereportoffungalnecrotizingotitismediaandmastoiditis AT mohsenrajati unusualpresentationofararediseaseacasereportoffungalnecrotizingotitismediaandmastoiditis AT hosseinzarrinfar unusualpresentationofararediseaseacasereportoffungalnecrotizingotitismediaandmastoiditis |