Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract Involvement

We describe a case of a 71-year-old male with an isolated recurrence of urothelial carcinoma in an ileal neobladder without involvement of the upper urinary tract or urethra. He was diagnosed with high grade urothelial carcinoma involving a bladder diverticulum with associated carcinoma in situ. He...

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Main Authors: Chirag P. Doshi, Guliz A. Barkan, Marcus L. Quek
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2019/8458706
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author Chirag P. Doshi
Guliz A. Barkan
Marcus L. Quek
author_facet Chirag P. Doshi
Guliz A. Barkan
Marcus L. Quek
author_sort Chirag P. Doshi
collection DOAJ
description We describe a case of a 71-year-old male with an isolated recurrence of urothelial carcinoma in an ileal neobladder without involvement of the upper urinary tract or urethra. He was diagnosed with high grade urothelial carcinoma involving a bladder diverticulum with associated carcinoma in situ. He underwent a radical cystectomy and orthotopic Studer ileal neobladder. On routine follow-up, 11 years following cystectomy, voided urine cytology was positive for high grade urothelial carcinoma. Further workup revealed normal upper urinary tracts, normal urethra, and a solitary lesion at the left anteroinferior wall of the neobladder. He subsequently underwent resection of the neobladder and conversion to an ileal conduit with pathology confirming the diagnosis of high grade urothelial carcinoma. Isolated recurrence of urothelial carcinoma within a neobladder without involvement of the upper urinary tract or urethra is rare. No guidelines exist regarding its management. Herein we present our management as well as the current literature published on this topic.
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spelling doaj-art-3f98e7691d0e466780bf77713141c8ff2025-02-03T06:11:31ZengWileyCase Reports in Urology2090-696X2090-69782019-01-01201910.1155/2019/84587068458706Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract InvolvementChirag P. Doshi0Guliz A. Barkan1Marcus L. Quek2Department of Urology, Loyola University Medical Center, Maywood, IL, USADepartment of Pathology, Loyola University Medical Center, Maywood, IL, USADepartment of Urology, Loyola University Medical Center, Maywood, IL, USAWe describe a case of a 71-year-old male with an isolated recurrence of urothelial carcinoma in an ileal neobladder without involvement of the upper urinary tract or urethra. He was diagnosed with high grade urothelial carcinoma involving a bladder diverticulum with associated carcinoma in situ. He underwent a radical cystectomy and orthotopic Studer ileal neobladder. On routine follow-up, 11 years following cystectomy, voided urine cytology was positive for high grade urothelial carcinoma. Further workup revealed normal upper urinary tracts, normal urethra, and a solitary lesion at the left anteroinferior wall of the neobladder. He subsequently underwent resection of the neobladder and conversion to an ileal conduit with pathology confirming the diagnosis of high grade urothelial carcinoma. Isolated recurrence of urothelial carcinoma within a neobladder without involvement of the upper urinary tract or urethra is rare. No guidelines exist regarding its management. Herein we present our management as well as the current literature published on this topic.http://dx.doi.org/10.1155/2019/8458706
spellingShingle Chirag P. Doshi
Guliz A. Barkan
Marcus L. Quek
Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract Involvement
Case Reports in Urology
title Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract Involvement
title_full Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract Involvement
title_fullStr Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract Involvement
title_full_unstemmed Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract Involvement
title_short Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract Involvement
title_sort urothelial carcinoma recurrence in an orthotopic neobladder without urethral or upper urinary tract involvement
url http://dx.doi.org/10.1155/2019/8458706
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AT gulizabarkan urothelialcarcinomarecurrenceinanorthotopicneobladderwithouturethralorupperurinarytractinvolvement
AT marcuslquek urothelialcarcinomarecurrenceinanorthotopicneobladderwithouturethralorupperurinarytractinvolvement