Real-time genome imaging of host interactions in adeno-associated virus genome release
Summary: Adeno-associated virus (AAVs) with a self-complementary genome (sc) comprising a gene of interest are used in gene therapy. Their efficiency is limited but the molecular factors contributing to this restriction are poorly understood. We utilized scAAV2 containing a fluorescent protein-bindi...
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| Main Authors: | Luisa F. Bustamante-Jaramillo, Lei Yue, Joshua Fingal, Gustaf Rydell, Maria Johansson, Tomas Edreira, Oliver J. Müller, Susanne Hille, Martin Müller, Franck Gallardo, Qingxin Chen, Marie-Lise Blondot, Michael Kann |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004225008855 |
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