Integrated bioinformatics analysis identifies CHAD association with osteoporosis and in vitro chondrogenic effects of Wogonin

Integrated bioinformatics analysis identifies CHAD association with osteoporosis and in vitro chondrogenic effects of Wogonin

Abstract Osteoporosis (OP), characterized by reduced bone density and increased fracture risk. Current therapies have limitations due to side effects and variable efficacy, necessitating exploration of novel therapeutic targets and alternatives like Traditional Chinese Medicine (TCM). The molecular...

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Bibliographic Details
Main Authors: Keng-Fu Lan, Wei-Hsiang Su, Yongjin Zhong, Yan Wu, Siqi Ye, Dan He, Yancheng Lai, Charles C. N. Wang, Anchun Mo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Osteoporosis
Traditional Chinese medicine
Bioinformatics
Molecular Docking
Wogonin
Online Access:https://doi.org/10.1038/s41598-025-05861-w
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