Radiosensitizing effects of miR‐18a‐5p on lung cancer stem‐like cells via downregulating both ATM and HIF‐1α

Radiosensitizing effects of miR‐18a‐5p on lung cancer stem‐like cells via downregulating both ATM and HIF‐1α

Abstract Lung cancer is one of the main causes of cancer mortality globally. Most patients received radiotherapy during the course of disease. However, radioresistance generally occurs in the majority of these patients, leading to poor curative effect, and the underlying mechanism remains unclear. I...

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Bibliographic Details
Main Authors: Xu Chen, Lei Wu, Dezhi Li, Yanmei Xu, Luping Zhang, Kai Niu, Rui Kong, Jiaoyang Gu, Zihan Xu, Zhengtang Chen, Jianguo Sun
Format: Article
Language:English
Published: Wiley 2018-08-01
Series:Cancer Medicine
Subjects:
DNA repair
lung adenocarcinoma
microRNAs
plasma biomarker
radiosensitivity
stem‐like cells
Online Access:https://doi.org/10.1002/cam4.1527
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