Immunophenotype-guided interpretable radiomics model for predicting neoadjuvant anti-PD-1 response in stage III–IV d-MMR/MSI-H colorectal cancer

Immunophenotype-guided interpretable radiomics model for predicting neoadjuvant anti-PD-1 response in stage III–IV d-MMR/MSI-H colorectal cancer

Background Neoadjuvant immunotherapy significantly improves the pathological complete response (pCR) rate in colorectal cancer (CRC). However, the lack of reliable tools to accurately identify responders remains a key barrier to its widespread clinical adoption. This study aimed to develop an interp...

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Main Authors: Xuan Zhang, Zhenhui Li, Yiwen Zhang, Yanli Li, Xi Zhong, Wenjing Jiang, Xiaobo Chen, Zaiyi Liu, Liebin Huang, Caixia Zhang, Lizhu Liu, Ruimin You, Xiaoping Yi
Format: Article
Language:English
Published: BMJ Publishing Group 2025-08-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/8/e011569.full
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