Unravelling the impact of linear energy transfer on micronuclei induction from proton and photon irradiation

Unravelling the impact of linear energy transfer on micronuclei induction from proton and photon irradiation

Abstract Micronucleus (MN) formation has a strong link to radiation damage and is a common bio-dosimeter for acute radiation exposures. The percentage of cells containing MN (PCMN) has a strong relationship with dose, however variation between previous studies has made understanding the effect of li...

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Bibliographic Details
Main Authors: Charlotte J. Heaven, John-William Warmenhoven, Amy L. Chadwick, Elham Santina, Jamie Honeychurch, Christine K. Schmidt, Karen J. Kirkby, Michael J. Merchant, Nicholas T. Henthorn
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Micronuclei
cytochalasin-B
Radiotherapy
Proton therapy, DNA damage
Online Access:https://doi.org/10.1038/s41598-025-09763-9
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