Priapism following a juvenile Russell's viper bite: An unusual case report.
Following a bite from a juvenile Russell's viper (Daboia russelii), a priapism (painful erection) developed rapidly in a 16-year-old male and only subsided after administration of antivenom 3 hours later. Potential mechanisms for this snakebite-induced priapism are unclear but likely due to ven...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-03-01
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| Series: | PLoS Neglected Tropical Diseases |
| Online Access: | https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0009242&type=printable |
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| author | Subramanian Senthilkumaran Harry F Williams Ketan Patel Steven A Trim Ponniah Thirumalaikolundusubramanian Sakthivel Vaiyapuri |
| author_facet | Subramanian Senthilkumaran Harry F Williams Ketan Patel Steven A Trim Ponniah Thirumalaikolundusubramanian Sakthivel Vaiyapuri |
| author_sort | Subramanian Senthilkumaran |
| collection | DOAJ |
| description | Following a bite from a juvenile Russell's viper (Daboia russelii), a priapism (painful erection) developed rapidly in a 16-year-old male and only subsided after administration of antivenom 3 hours later. Potential mechanisms for this snakebite-induced priapism are unclear but likely due to venom toxins causing nitric oxide (NO) release and subsequent vasodilation of endothelium in the corpus cavernosum, although the possible involvement of other mechanisms cannot be ruled out. We strongly believe that this unusual case report may lead to further scientific research in order to improve the clinical understanding of the pathophysiology of envenomation due to Russell's viper bites. Although it is too early to speculate, further research may also discover the possibilities of developing venom-based candidate molecules to treat sexual dysfunction in males and females. |
| format | Article |
| id | doaj-art-3f89543c4cc8404eac2a28537151feb4 |
| institution | OA Journals |
| issn | 1935-2727 1935-2735 |
| language | English |
| publishDate | 2021-03-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Neglected Tropical Diseases |
| spelling | doaj-art-3f89543c4cc8404eac2a28537151feb42025-08-20T02:00:54ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352021-03-01153e000924210.1371/journal.pntd.0009242Priapism following a juvenile Russell's viper bite: An unusual case report.Subramanian SenthilkumaranHarry F WilliamsKetan PatelSteven A TrimPonniah ThirumalaikolundusubramanianSakthivel VaiyapuriFollowing a bite from a juvenile Russell's viper (Daboia russelii), a priapism (painful erection) developed rapidly in a 16-year-old male and only subsided after administration of antivenom 3 hours later. Potential mechanisms for this snakebite-induced priapism are unclear but likely due to venom toxins causing nitric oxide (NO) release and subsequent vasodilation of endothelium in the corpus cavernosum, although the possible involvement of other mechanisms cannot be ruled out. We strongly believe that this unusual case report may lead to further scientific research in order to improve the clinical understanding of the pathophysiology of envenomation due to Russell's viper bites. Although it is too early to speculate, further research may also discover the possibilities of developing venom-based candidate molecules to treat sexual dysfunction in males and females.https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0009242&type=printable |
| spellingShingle | Subramanian Senthilkumaran Harry F Williams Ketan Patel Steven A Trim Ponniah Thirumalaikolundusubramanian Sakthivel Vaiyapuri Priapism following a juvenile Russell's viper bite: An unusual case report. PLoS Neglected Tropical Diseases |
| title | Priapism following a juvenile Russell's viper bite: An unusual case report. |
| title_full | Priapism following a juvenile Russell's viper bite: An unusual case report. |
| title_fullStr | Priapism following a juvenile Russell's viper bite: An unusual case report. |
| title_full_unstemmed | Priapism following a juvenile Russell's viper bite: An unusual case report. |
| title_short | Priapism following a juvenile Russell's viper bite: An unusual case report. |
| title_sort | priapism following a juvenile russell s viper bite an unusual case report |
| url | https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0009242&type=printable |
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