The CHESS Protocol: A Mixed-Methods Evaluation of an HPV Screening Intervention for Women Living With HIV in Nigeria
ObjectivesIn this protocol, we describe a planned intervention to adapt the Mother Mentor (MoMent) peer support program for women living with HIV (WLWH). WLWH face a six-fold higher risk of cervical cancer, yet screening and treatment rates remain low in Nigeria.MethodsUsing an implementation scienc...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
|
| Series: | International Journal of Public Health |
| Subjects: | |
| Online Access: | https://www.ssph-journal.org/articles/10.3389/ijph.2025.1608716/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849405167100755968 |
|---|---|
| author | Olabanjo Ogunsola Laura M. Gaydos Oluseye Ajayi Maria Dieci Nadi Kaonga Olutosin Awolude Priscilla Ezemelue Tyree Staple Kabiru Salami Ifeoma Idigbe Oliver Ezechi Lisa Flowers |
| author_facet | Olabanjo Ogunsola Laura M. Gaydos Oluseye Ajayi Maria Dieci Nadi Kaonga Olutosin Awolude Priscilla Ezemelue Tyree Staple Kabiru Salami Ifeoma Idigbe Oliver Ezechi Lisa Flowers |
| author_sort | Olabanjo Ogunsola |
| collection | DOAJ |
| description | ObjectivesIn this protocol, we describe a planned intervention to adapt the Mother Mentor (MoMent) peer support program for women living with HIV (WLWH). WLWH face a six-fold higher risk of cervical cancer, yet screening and treatment rates remain low in Nigeria.MethodsUsing an implementation science approach, we will engage key stakeholders—including ministries of health, NACA, professional bodies, WLWH, Mentor Mothers, healthcare providers, and development partners (e.g., WHO, US CDC, USAID)—through deliberative democracy to adapt and expand MoMent for home-based HPV screening and follow-up treatment. We will pilot the adapted MoMent HIV+HCC program with 1,500 women in 15 health facilities across Nigeria’s five geopolitical zones. The RE-AIM framework will guide evaluation of reach, adoption, fidelity, effectiveness, and sustainability.ResultsThis study is designed to contribute to WHO’s global strategy to eliminate cervical cancer by improving access to home-based screening and care in low-resource settings.ConclusionFindings will inform national HPV prevention efforts and may drive broader integration into Nigeria’s cervical cancer program.Clinical Trial RegistrationClinicaltrials.gov, identifier NCT06751030. |
| format | Article |
| id | doaj-art-3f87abf2ed2e48678c356d39b5645fdf |
| institution | Kabale University |
| issn | 1661-8564 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | International Journal of Public Health |
| spelling | doaj-art-3f87abf2ed2e48678c356d39b5645fdf2025-08-20T03:36:45ZengFrontiers Media S.A.International Journal of Public Health1661-85642025-08-017010.3389/ijph.2025.16087161608716The CHESS Protocol: A Mixed-Methods Evaluation of an HPV Screening Intervention for Women Living With HIV in NigeriaOlabanjo Ogunsola0Laura M. Gaydos1Oluseye Ajayi2Maria Dieci3Nadi Kaonga4Olutosin Awolude5Priscilla Ezemelue6Tyree Staple7Kabiru Salami8Ifeoma Idigbe9Oliver Ezechi10Lisa Flowers11APIN Public Health Initiatives, Abuja, NigeriaDepartment of Health Policy and Management, Emory University, Atlanta, GA, United StatesAPIN Public Health Initiatives, Abuja, NigeriaDepartment of Health Policy and Management, Emory University, Atlanta, GA, United StatesDepartment of Gynecology and Obstetrics, Emory University, Atlanta, GA, United StatesObstetrics and Gynecology Department, College of Medicine, University of Ibadan, Ibadan, NigeriaClinical Sciences Department, Nigerian Institute of Medical Research, Lagos, NigeriaDepartment of Gynecology and Obstetrics, Emory University, Atlanta, GA, United StatesDepartment of Sociology, Medical Sociology, University of Ibadan, Ibadan, NigeriaClinical Sciences Department, Nigerian Institute of Medical Research, Lagos, NigeriaClinical Sciences Department, Nigerian Institute of Medical Research, Lagos, NigeriaDepartment of Gynecology and Obstetrics, Emory University, Atlanta, GA, United StatesObjectivesIn this protocol, we describe a planned intervention to adapt the Mother Mentor (MoMent) peer support program for women living with HIV (WLWH). WLWH face a six-fold higher risk of cervical cancer, yet screening and treatment rates remain low in Nigeria.MethodsUsing an implementation science approach, we will engage key stakeholders—including ministries of health, NACA, professional bodies, WLWH, Mentor Mothers, healthcare providers, and development partners (e.g., WHO, US CDC, USAID)—through deliberative democracy to adapt and expand MoMent for home-based HPV screening and follow-up treatment. We will pilot the adapted MoMent HIV+HCC program with 1,500 women in 15 health facilities across Nigeria’s five geopolitical zones. The RE-AIM framework will guide evaluation of reach, adoption, fidelity, effectiveness, and sustainability.ResultsThis study is designed to contribute to WHO’s global strategy to eliminate cervical cancer by improving access to home-based screening and care in low-resource settings.ConclusionFindings will inform national HPV prevention efforts and may drive broader integration into Nigeria’s cervical cancer program.Clinical Trial RegistrationClinicaltrials.gov, identifier NCT06751030.https://www.ssph-journal.org/articles/10.3389/ijph.2025.1608716/fullimplementation sciencecervical cancerHPVwomen living with HIVlay-healthself-collection |
| spellingShingle | Olabanjo Ogunsola Laura M. Gaydos Oluseye Ajayi Maria Dieci Nadi Kaonga Olutosin Awolude Priscilla Ezemelue Tyree Staple Kabiru Salami Ifeoma Idigbe Oliver Ezechi Lisa Flowers The CHESS Protocol: A Mixed-Methods Evaluation of an HPV Screening Intervention for Women Living With HIV in Nigeria International Journal of Public Health implementation science cervical cancer HPV women living with HIV lay-health self-collection |
| title | The CHESS Protocol: A Mixed-Methods Evaluation of an HPV Screening Intervention for Women Living With HIV in Nigeria |
| title_full | The CHESS Protocol: A Mixed-Methods Evaluation of an HPV Screening Intervention for Women Living With HIV in Nigeria |
| title_fullStr | The CHESS Protocol: A Mixed-Methods Evaluation of an HPV Screening Intervention for Women Living With HIV in Nigeria |
| title_full_unstemmed | The CHESS Protocol: A Mixed-Methods Evaluation of an HPV Screening Intervention for Women Living With HIV in Nigeria |
| title_short | The CHESS Protocol: A Mixed-Methods Evaluation of an HPV Screening Intervention for Women Living With HIV in Nigeria |
| title_sort | chess protocol a mixed methods evaluation of an hpv screening intervention for women living with hiv in nigeria |
| topic | implementation science cervical cancer HPV women living with HIV lay-health self-collection |
| url | https://www.ssph-journal.org/articles/10.3389/ijph.2025.1608716/full |
| work_keys_str_mv | AT olabanjoogunsola thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT lauramgaydos thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT oluseyeajayi thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT mariadieci thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT nadikaonga thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT olutosinawolude thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT priscillaezemelue thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT tyreestaple thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT kabirusalami thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT ifeomaidigbe thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT oliverezechi thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT lisaflowers thechessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT olabanjoogunsola chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT lauramgaydos chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT oluseyeajayi chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT mariadieci chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT nadikaonga chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT olutosinawolude chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT priscillaezemelue chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT tyreestaple chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT kabirusalami chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT ifeomaidigbe chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT oliverezechi chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria AT lisaflowers chessprotocolamixedmethodsevaluationofanhpvscreeninginterventionforwomenlivingwithhivinnigeria |