Exploring the mechanisms and current status of acupuncture in alleviating tumor metabolism and associated diseases: Insights from the central nervous system and immune microenvironment

Acupuncture, as a traditional Chinese medical treatment, has garnered increasing attention in recent years in fields such as tumor metabolism, the central nervous system, and the immune microenvironment. This paper aims to explore the fundamental principles, mechanisms, and research status of acupun...

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Main Authors: Yuwei Chen, Mingzhu Li, Kaixin Guo
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:SLAS Technology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2472630324000906
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author Yuwei Chen
Mingzhu Li
Kaixin Guo
author_facet Yuwei Chen
Mingzhu Li
Kaixin Guo
author_sort Yuwei Chen
collection DOAJ
description Acupuncture, as a traditional Chinese medical treatment, has garnered increasing attention in recent years in fields such as tumor metabolism, the central nervous system, and the immune microenvironment. This paper aims to explore the fundamental principles, mechanisms, and research status of acupuncture therapy for tumor-related diseases. Firstly, we introduce the basic principles of acupuncture therapy, including the theories of meridians and its theoretical basis in tumor treatment. Secondly, we systematically review the mechanisms of acupuncture therapy for tumor-related diseases, discussing how acupuncture alleviates side effects such as pain, depression, fatigue, and gastrointestinal discomfort caused by conventional treatments through modulation of the immune microenvironment, central nervous system, and endocrine system. Subsequently, we discuss the current research status of acupuncture therapy for tumor-related diseases, as well as the application of current research methods and technologies in elucidating acupuncture mechanisms. Additionally, by combining clinical practice with different types of tumor-related diseases as experimental subjects, we demonstrate the application effectiveness and clinical practice experience of acupuncture in tumor treatment. Finally, a comprehensive assessment of acupuncture therapy for tumor-related diseases is provided, summarizing its limitations and prospecting future directions, including interdisciplinary collaboration and personalized treatment. In conclusion, acupuncture, as a feasible adjunctive therapy, is closely related to the central nervous system and the immune microenvironment, holding potential significant value in tumor treatment.
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spelling doaj-art-3f8697aba36c41299c6ced9b4ca704fd2025-08-20T01:57:52ZengElsevierSLAS Technology2472-63032024-12-0129610020810.1016/j.slast.2024.100208Exploring the mechanisms and current status of acupuncture in alleviating tumor metabolism and associated diseases: Insights from the central nervous system and immune microenvironmentYuwei Chen0Mingzhu Li1Kaixin Guo2First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan 250000, ChinaFirst Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan 250000, ChinaDepartment of Acupuncture, Shandong University of Traditional Chinese Medicine, Jinan 250000, China; Corresponding author.Acupuncture, as a traditional Chinese medical treatment, has garnered increasing attention in recent years in fields such as tumor metabolism, the central nervous system, and the immune microenvironment. This paper aims to explore the fundamental principles, mechanisms, and research status of acupuncture therapy for tumor-related diseases. Firstly, we introduce the basic principles of acupuncture therapy, including the theories of meridians and its theoretical basis in tumor treatment. Secondly, we systematically review the mechanisms of acupuncture therapy for tumor-related diseases, discussing how acupuncture alleviates side effects such as pain, depression, fatigue, and gastrointestinal discomfort caused by conventional treatments through modulation of the immune microenvironment, central nervous system, and endocrine system. Subsequently, we discuss the current research status of acupuncture therapy for tumor-related diseases, as well as the application of current research methods and technologies in elucidating acupuncture mechanisms. Additionally, by combining clinical practice with different types of tumor-related diseases as experimental subjects, we demonstrate the application effectiveness and clinical practice experience of acupuncture in tumor treatment. Finally, a comprehensive assessment of acupuncture therapy for tumor-related diseases is provided, summarizing its limitations and prospecting future directions, including interdisciplinary collaboration and personalized treatment. In conclusion, acupuncture, as a feasible adjunctive therapy, is closely related to the central nervous system and the immune microenvironment, holding potential significant value in tumor treatment.http://www.sciencedirect.com/science/article/pii/S2472630324000906AcupunctureTumor-related diseasesTumor metabolismCentral nervous systemEndocrine SystemImmune microenvironment
spellingShingle Yuwei Chen
Mingzhu Li
Kaixin Guo
Exploring the mechanisms and current status of acupuncture in alleviating tumor metabolism and associated diseases: Insights from the central nervous system and immune microenvironment
SLAS Technology
Acupuncture
Tumor-related diseases
Tumor metabolism
Central nervous system
Endocrine System
Immune microenvironment
title Exploring the mechanisms and current status of acupuncture in alleviating tumor metabolism and associated diseases: Insights from the central nervous system and immune microenvironment
title_full Exploring the mechanisms and current status of acupuncture in alleviating tumor metabolism and associated diseases: Insights from the central nervous system and immune microenvironment
title_fullStr Exploring the mechanisms and current status of acupuncture in alleviating tumor metabolism and associated diseases: Insights from the central nervous system and immune microenvironment
title_full_unstemmed Exploring the mechanisms and current status of acupuncture in alleviating tumor metabolism and associated diseases: Insights from the central nervous system and immune microenvironment
title_short Exploring the mechanisms and current status of acupuncture in alleviating tumor metabolism and associated diseases: Insights from the central nervous system and immune microenvironment
title_sort exploring the mechanisms and current status of acupuncture in alleviating tumor metabolism and associated diseases insights from the central nervous system and immune microenvironment
topic Acupuncture
Tumor-related diseases
Tumor metabolism
Central nervous system
Endocrine System
Immune microenvironment
url http://www.sciencedirect.com/science/article/pii/S2472630324000906
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AT mingzhuli exploringthemechanismsandcurrentstatusofacupunctureinalleviatingtumormetabolismandassociateddiseasesinsightsfromthecentralnervoussystemandimmunemicroenvironment
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