A Rare Case of Uterine-Origin Vulvar Leiomyoma Occurring in a Juvenile Girl: Case Report and Literature Review
Leiomyoma arising from the vulva is very rare, and it is difficult to differentiate it from a Bartholin gland cyst and aggressive angiomyxomas. We report a case of vulvar leiomyoma in a juvenile girl. The patient, a 16-year-old female, had noted a tender subcutaneous nodule on the right vulva for 2...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/crog/8874924 |
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| Summary: | Leiomyoma arising from the vulva is very rare, and it is difficult to differentiate it from a Bartholin gland cyst and aggressive angiomyxomas. We report a case of vulvar leiomyoma in a juvenile girl. The patient, a 16-year-old female, had noted a tender subcutaneous nodule on the right vulva for 2 years. At first, a Bartholin gland cyst was suspected, and she was prescribed antibiotics. However, because of persistent symptoms, the patient was referred to our clinic for further examination. An MRI scan suspected a mesenchymal tumor, and surgical resection was performed. Tumor cells were diffusely positive for anti-smooth muscle antibodies, HHF35, and Desmin, and leiomyoma was suspected. Immunostaining tests were negative for estrogen receptor and positive for progesterone receptor. The patient exhibited an excellent postoperative course with no evidence of recurrence at the latest follow-up. Surgical resection is the only curative treatment, and long-term follow-up is recommended because of rare reports of recurrence. |
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| ISSN: | 2090-6692 |