Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?
Although there are abundant data highlighting the safety and efficacy of direct oral anticoagulants, to date, recent guidelines have limited their use to stroke prevention in patients with non-valvular AF, as well as in the prevention and treatment of venous thromboembolism and pulmonary embolism. E...
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| Format: | Article |
| Language: | English |
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Radcliffe Medical Media
2020-02-01
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| Series: | European Cardiology Review |
| Online Access: | https://www.ecrjournal.com/articleindex/ecr.2019.1.3 |
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| author | Mahmoud Abdelnabi Abdallah Almaghraby Yehia Saleh |
| author_facet | Mahmoud Abdelnabi Abdallah Almaghraby Yehia Saleh |
| author_sort | Mahmoud Abdelnabi |
| collection | DOAJ |
| description | Although there are abundant data highlighting the safety and efficacy of direct oral anticoagulants, to date, recent guidelines have limited their use to stroke prevention in patients with non-valvular AF, as well as in the prevention and treatment of venous thromboembolism and pulmonary embolism. Encouraging data about the off-label use of direct oral anticoagulants have been shown in several other indications, such as intracardiac thrombi, left ventricular thrombi and left atrial appendage, but a large sector of patients are still not addressed, such as valvular and prosthetic patients. |
| format | Article |
| id | doaj-art-3f7a0c0fc0ee4d7b98debbb323263092 |
| institution | OA Journals |
| issn | 1758-3756 1758-3764 |
| language | English |
| publishDate | 2020-02-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | European Cardiology Review |
| spelling | doaj-art-3f7a0c0fc0ee4d7b98debbb3232630922025-08-20T01:56:38ZengRadcliffe Medical MediaEuropean Cardiology Review1758-37561758-37642020-02-011510.15420/ecr.2019.1.3Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves?Mahmoud Abdelnabi0Abdallah Almaghraby1Yehia Saleh2Cardiology and Angiology Unit, Department of Clinical and Experimental Internal Medicine, Medical Research Institute, University of Alexandria, EgyptDepartment of Cardiology, Faculty of Medicine, University of Alexandria, EgyptDepartment of Cardiology, Faculty of Medicine, University of Alexandria, Egypt; Michigan State University, East Lansing, MI, USAlthough there are abundant data highlighting the safety and efficacy of direct oral anticoagulants, to date, recent guidelines have limited their use to stroke prevention in patients with non-valvular AF, as well as in the prevention and treatment of venous thromboembolism and pulmonary embolism. Encouraging data about the off-label use of direct oral anticoagulants have been shown in several other indications, such as intracardiac thrombi, left ventricular thrombi and left atrial appendage, but a large sector of patients are still not addressed, such as valvular and prosthetic patients.https://www.ecrjournal.com/articleindex/ecr.2019.1.3 |
| spellingShingle | Mahmoud Abdelnabi Abdallah Almaghraby Yehia Saleh Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves? European Cardiology Review |
| title | Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves? |
| title_full | Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves? |
| title_fullStr | Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves? |
| title_full_unstemmed | Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves? |
| title_short | Will Direct Oral Anticoagulants Have a Chance in Prosthetic Valves? |
| title_sort | will direct oral anticoagulants have a chance in prosthetic valves |
| url | https://www.ecrjournal.com/articleindex/ecr.2019.1.3 |
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