THE EFFICACY AND SAFETY OF TOPICAL TRIAMCINOLONE IN REDUCING URETHRAL STRICTURE RECURRENCE FOLLOWING INTERNAL URETHROTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Objective: This systematic review aims to determine the efficacy and safety of topical triamcinolone in reducing urethral stricture recurrence following internal urethrotomy procedures. Material & Methods: A systematic literature search was performed in Cochrane Library, PubMed and Google Schol...

Full description

Saved in:
Bibliographic Details
Main Authors: Moh. Alwi Hamzah, Muhammad Risan, Muhammad Jabir
Format: Article
Language:English
Published: IKATAN AHLI UROLOGI INDONESIA 2025-01-01
Series:Jurnal Urologi Indonesia
Subjects:
Online Access:http://juri.urologi.or.id/juri/article/view/915
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1841554173097672704
author Moh. Alwi Hamzah
Muhammad Risan
Muhammad Jabir
author_facet Moh. Alwi Hamzah
Muhammad Risan
Muhammad Jabir
author_sort Moh. Alwi Hamzah
collection DOAJ
description Objective: This systematic review aims to determine the efficacy and safety of topical triamcinolone in reducing urethral stricture recurrence following internal urethrotomy procedures. Material & Methods: A systematic literature search was performed in Cochrane Library, PubMed and Google Scholar with the related keywords. The statistical analysis was conducted using a Review Manager v.5.4.1. Results: We identified 6 RCTs with a total of 316 patients diagnosed with urethral stricture undergoing internal urethrotomy. The statistical analysis appeared to lower the recurrence rate significantly in patients undergoing internal urethrotomy with the adjuvant therapy of topical triamcinolone (RR 0.55, 95% CI 0.38 – 0.78, p = 0.0008). Conclusion: Additional treatment with topical triamcinolone has the benefit of declining the recurrence rate of urethral stricture following internal urethrotomy. Keywords: Triamcinolone, urethral stricture, internal urethrotomy.
format Article
id doaj-art-3f79821371c94505ba64aea3b3677662
institution Kabale University
issn 0853-442X
2355-1402
language English
publishDate 2025-01-01
publisher IKATAN AHLI UROLOGI INDONESIA
record_format Article
series Jurnal Urologi Indonesia
spelling doaj-art-3f79821371c94505ba64aea3b36776622025-01-08T17:22:53ZengIKATAN AHLI UROLOGI INDONESIAJurnal Urologi Indonesia0853-442X2355-14022025-01-0132110.32421/juri.v32i1.915THE EFFICACY AND SAFETY OF TOPICAL TRIAMCINOLONE IN REDUCING URETHRAL STRICTURE RECURRENCE FOLLOWING INTERNAL URETHROTOMY: A SYSTEMATIC REVIEW AND META-ANALYSISMoh. Alwi Hamzah0Muhammad Risan1Muhammad Jabir2General Practitioner, Bahteramas General Hospital, Kendari.Department of Urology, Hermina Hospital, Kendari.Department of Urology, Bhayangkara Hospital, Kendari. Objective: This systematic review aims to determine the efficacy and safety of topical triamcinolone in reducing urethral stricture recurrence following internal urethrotomy procedures. Material & Methods: A systematic literature search was performed in Cochrane Library, PubMed and Google Scholar with the related keywords. The statistical analysis was conducted using a Review Manager v.5.4.1. Results: We identified 6 RCTs with a total of 316 patients diagnosed with urethral stricture undergoing internal urethrotomy. The statistical analysis appeared to lower the recurrence rate significantly in patients undergoing internal urethrotomy with the adjuvant therapy of topical triamcinolone (RR 0.55, 95% CI 0.38 – 0.78, p = 0.0008). Conclusion: Additional treatment with topical triamcinolone has the benefit of declining the recurrence rate of urethral stricture following internal urethrotomy. Keywords: Triamcinolone, urethral stricture, internal urethrotomy. http://juri.urologi.or.id/juri/article/view/915Triamcinoloneurethral strictureinternal urethrotomy
spellingShingle Moh. Alwi Hamzah
Muhammad Risan
Muhammad Jabir
THE EFFICACY AND SAFETY OF TOPICAL TRIAMCINOLONE IN REDUCING URETHRAL STRICTURE RECURRENCE FOLLOWING INTERNAL URETHROTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS
Jurnal Urologi Indonesia
Triamcinolone
urethral stricture
internal urethrotomy
title THE EFFICACY AND SAFETY OF TOPICAL TRIAMCINOLONE IN REDUCING URETHRAL STRICTURE RECURRENCE FOLLOWING INTERNAL URETHROTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS
title_full THE EFFICACY AND SAFETY OF TOPICAL TRIAMCINOLONE IN REDUCING URETHRAL STRICTURE RECURRENCE FOLLOWING INTERNAL URETHROTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS
title_fullStr THE EFFICACY AND SAFETY OF TOPICAL TRIAMCINOLONE IN REDUCING URETHRAL STRICTURE RECURRENCE FOLLOWING INTERNAL URETHROTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS
title_full_unstemmed THE EFFICACY AND SAFETY OF TOPICAL TRIAMCINOLONE IN REDUCING URETHRAL STRICTURE RECURRENCE FOLLOWING INTERNAL URETHROTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS
title_short THE EFFICACY AND SAFETY OF TOPICAL TRIAMCINOLONE IN REDUCING URETHRAL STRICTURE RECURRENCE FOLLOWING INTERNAL URETHROTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS
title_sort efficacy and safety of topical triamcinolone in reducing urethral stricture recurrence following internal urethrotomy a systematic review and meta analysis
topic Triamcinolone
urethral stricture
internal urethrotomy
url http://juri.urologi.or.id/juri/article/view/915
work_keys_str_mv AT mohalwihamzah theefficacyandsafetyoftopicaltriamcinoloneinreducingurethralstricturerecurrencefollowinginternalurethrotomyasystematicreviewandmetaanalysis
AT muhammadrisan theefficacyandsafetyoftopicaltriamcinoloneinreducingurethralstricturerecurrencefollowinginternalurethrotomyasystematicreviewandmetaanalysis
AT muhammadjabir theefficacyandsafetyoftopicaltriamcinoloneinreducingurethralstricturerecurrencefollowinginternalurethrotomyasystematicreviewandmetaanalysis
AT mohalwihamzah efficacyandsafetyoftopicaltriamcinoloneinreducingurethralstricturerecurrencefollowinginternalurethrotomyasystematicreviewandmetaanalysis
AT muhammadrisan efficacyandsafetyoftopicaltriamcinoloneinreducingurethralstricturerecurrencefollowinginternalurethrotomyasystematicreviewandmetaanalysis
AT muhammadjabir efficacyandsafetyoftopicaltriamcinoloneinreducingurethralstricturerecurrencefollowinginternalurethrotomyasystematicreviewandmetaanalysis