Favorable Outcome of Severe Poisoning by Snake Green Mamba (<i>Dendroaspis viridis</i>) Clinical Case

This clinical case of acute poisoning due to bite of snake Dendroaspis viridis seems interesting to share because of its rare incidence inRussiaand management peculiarities: the critical care was conducted without specific antidote therapy due to absence of the antidote.The prevailing clinical prese...

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Main Authors: A. R. Nasibullina, A. N. Lodyagin, V. A. Vdovin, N. E. Filippova, B. V. Batotsyrenov, S. I. Glushkov
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2019-04-01
Series:Общая реаниматология
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Online Access:https://www.reanimatology.com/rmt/article/view/1744
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author A. R. Nasibullina
A. N. Lodyagin
V. A. Vdovin
N. E. Filippova
B. V. Batotsyrenov
S. I. Glushkov
author_facet A. R. Nasibullina
A. N. Lodyagin
V. A. Vdovin
N. E. Filippova
B. V. Batotsyrenov
S. I. Glushkov
author_sort A. R. Nasibullina
collection DOAJ
description This clinical case of acute poisoning due to bite of snake Dendroaspis viridis seems interesting to share because of its rare incidence inRussiaand management peculiarities: the critical care was conducted without specific antidote therapy due to absence of the antidote.The prevailing clinical presentation included signs of toxic myopathy combined with paresis of skeletal and breathing muscles that led to development of acute respiratory failure and metabolic disorders. The processes described were induced by the action of snake poison dendrotoxins featuring the activities of potassium channel blockers and acetyl cholinesterase inhibitors.The proper critical care included conduct of syndrome therapy aimed at maintaining life support systems adequately to condition (replacement of the breathing and circulation functions), antibiotic therapy and desensitizing treatment and metabolic care by administration of drugs characterized by antihypoxant/antioxidant mechanism of action.The comprehensive therapy applied has resulted in a favorable outcome of acute poisoning by snake green mamba without development of possible complications even when the specific antidote drug has not been included into the treatment protocol.
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id doaj-art-3f75aa33ef6e454dab1d5c3f12a1b212
institution Kabale University
issn 1813-9779
2411-7110
language English
publishDate 2019-04-01
publisher Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
record_format Article
series Общая реаниматология
spelling doaj-art-3f75aa33ef6e454dab1d5c3f12a1b2122025-08-20T03:35:07ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102019-04-01152212610.15360/1813-9779-2019-2-21-261680Favorable Outcome of Severe Poisoning by Snake Green Mamba (<i>Dendroaspis viridis</i>) Clinical CaseA. R. Nasibullina0A. N. Lodyagin1V. A. Vdovin2N. E. Filippova3B. V. Batotsyrenov4S. I. Glushkov5City Clinical Hospital №7I. I. Dzhanelidze Saint-Petersburg Research Institute of Emergency MedicineCity Clinical Hospital №7I. I. Dzhanelidze Saint-Petersburg Research Institute of Emergency MedicineI. I. Dzhanelidze Saint-Petersburg Research Institute of Emergency MedicineI. I. Dzhanelidze Saint-Petersburg Research Institute of Emergency MedicineThis clinical case of acute poisoning due to bite of snake Dendroaspis viridis seems interesting to share because of its rare incidence inRussiaand management peculiarities: the critical care was conducted without specific antidote therapy due to absence of the antidote.The prevailing clinical presentation included signs of toxic myopathy combined with paresis of skeletal and breathing muscles that led to development of acute respiratory failure and metabolic disorders. The processes described were induced by the action of snake poison dendrotoxins featuring the activities of potassium channel blockers and acetyl cholinesterase inhibitors.The proper critical care included conduct of syndrome therapy aimed at maintaining life support systems adequately to condition (replacement of the breathing and circulation functions), antibiotic therapy and desensitizing treatment and metabolic care by administration of drugs characterized by antihypoxant/antioxidant mechanism of action.The comprehensive therapy applied has resulted in a favorable outcome of acute poisoning by snake green mamba without development of possible complications even when the specific antidote drug has not been included into the treatment protocol.https://www.reanimatology.com/rmt/article/view/1744acute poisoningpoisonssnake bitesgreen mambametabolic disorderscytoflavinreamberin
spellingShingle A. R. Nasibullina
A. N. Lodyagin
V. A. Vdovin
N. E. Filippova
B. V. Batotsyrenov
S. I. Glushkov
Favorable Outcome of Severe Poisoning by Snake Green Mamba (<i>Dendroaspis viridis</i>) Clinical Case
Общая реаниматология
acute poisoning
poisons
snake bites
green mamba
metabolic disorders
cytoflavin
reamberin
title Favorable Outcome of Severe Poisoning by Snake Green Mamba (<i>Dendroaspis viridis</i>) Clinical Case
title_full Favorable Outcome of Severe Poisoning by Snake Green Mamba (<i>Dendroaspis viridis</i>) Clinical Case
title_fullStr Favorable Outcome of Severe Poisoning by Snake Green Mamba (<i>Dendroaspis viridis</i>) Clinical Case
title_full_unstemmed Favorable Outcome of Severe Poisoning by Snake Green Mamba (<i>Dendroaspis viridis</i>) Clinical Case
title_short Favorable Outcome of Severe Poisoning by Snake Green Mamba (<i>Dendroaspis viridis</i>) Clinical Case
title_sort favorable outcome of severe poisoning by snake green mamba i dendroaspis viridis i clinical case
topic acute poisoning
poisons
snake bites
green mamba
metabolic disorders
cytoflavin
reamberin
url https://www.reanimatology.com/rmt/article/view/1744
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AT anlodyagin favorableoutcomeofseverepoisoningbysnakegreenmambaidendroaspisviridisiclinicalcase
AT vavdovin favorableoutcomeofseverepoisoningbysnakegreenmambaidendroaspisviridisiclinicalcase
AT nefilippova favorableoutcomeofseverepoisoningbysnakegreenmambaidendroaspisviridisiclinicalcase
AT bvbatotsyrenov favorableoutcomeofseverepoisoningbysnakegreenmambaidendroaspisviridisiclinicalcase
AT siglushkov favorableoutcomeofseverepoisoningbysnakegreenmambaidendroaspisviridisiclinicalcase