Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion
The time course of changes in myocardial lipid peroxidation processes was studied in an experiment on albino male rats that had experienced 4-minute clinical death. There was an alternation of periods of a significant increase (minute 90, hours 3—6, and days 1—3 and 14) and a decrease (days 7, 21, a...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2006-12-01
|
| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1361 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849698698618994688 |
|---|---|
| author | V. T. Dolgikh F. I. Razgonov L. G. Shikunova |
| author_facet | V. T. Dolgikh F. I. Razgonov L. G. Shikunova |
| author_sort | V. T. Dolgikh |
| collection | DOAJ |
| description | The time course of changes in myocardial lipid peroxidation processes was studied in an experiment on albino male rats that had experienced 4-minute clinical death. There was an alternation of periods of a significant increase (minute 90, hours 3—6, and days 1—3 and 14) and a decrease (days 7, 21, and 30) in the rate of lipoprotein processes and corresponding changes in the content of lipid hydroperoxides and Schiff s bases. Activation of lipid peroxidation processes occurred with deficiency of bioantioxidants and with inhibition of enzymes that made antiradical and antiperoxide protection of cardiomyocytes.acute fatal hemorrhage; resuscitation; heart; lipid peroxidation |
| format | Article |
| id | doaj-art-3f6c964f943d424e8908a1a796d6be3b |
| institution | DOAJ |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2006-12-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-3f6c964f943d424e8908a1a796d6be3b2025-08-20T03:18:50ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102006-12-0126505410.15360/1813-9779-2006-6-50-541361Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac LesionV. T. Dolgikh0F. I. Razgonov1L. G. Shikunova2Department of Pathophysiology; Department of Military and Emergency Medicine, Omsk State Medical AcademyDepartment of Pathophysiology; Department of Military and Emergency Medicine, Omsk State Medical AcademyResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowThe time course of changes in myocardial lipid peroxidation processes was studied in an experiment on albino male rats that had experienced 4-minute clinical death. There was an alternation of periods of a significant increase (minute 90, hours 3—6, and days 1—3 and 14) and a decrease (days 7, 21, and 30) in the rate of lipoprotein processes and corresponding changes in the content of lipid hydroperoxides and Schiff s bases. Activation of lipid peroxidation processes occurred with deficiency of bioantioxidants and with inhibition of enzymes that made antiradical and antiperoxide protection of cardiomyocytes.acute fatal hemorrhage; resuscitation; heart; lipid peroxidationhttps://www.reanimatology.com/rmt/article/view/1361acute fatal hemorrhageresuscitationheartlipid peroxidation |
| spellingShingle | V. T. Dolgikh F. I. Razgonov L. G. Shikunova Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion Общая реаниматология acute fatal hemorrhage resuscitation heart lipid peroxidation |
| title | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
| title_full | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
| title_fullStr | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
| title_full_unstemmed | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
| title_short | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
| title_sort | acute fatal hemorrhage induced activation of lipid peroxidation processes and cardiac lesion |
| topic | acute fatal hemorrhage resuscitation heart lipid peroxidation |
| url | https://www.reanimatology.com/rmt/article/view/1361 |
| work_keys_str_mv | AT vtdolgikh acutefatalhemorrhageinducedactivationoflipidperoxidationprocessesandcardiaclesion AT firazgonov acutefatalhemorrhageinducedactivationoflipidperoxidationprocessesandcardiaclesion AT lgshikunova acutefatalhemorrhageinducedactivationoflipidperoxidationprocessesandcardiaclesion |