Inhibitory Impact of the Amino Benzoic Derivative DAB-2-28 on the Process of Epithelial–Mesenchymal Transition in Human Breast Cancer Cells

Inhibitory Impact of the Amino Benzoic Derivative DAB-2-28 on the Process of Epithelial–Mesenchymal Transition in Human Breast Cancer Cells

Macrophage-mediated inflammation is known to be involved in the epithelial–mesenchymal transition (EMT) of various types of cancer. This makes macrophage-derived inflammatory factors prime targets for the development of new treatments. This study uncovers the therapeutic potential and action mechani...

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Bibliographic Details
Main Authors: Laurie Fortin, Julie Girouard, Yassine Oufqir, Alexis Paquin, Francis Cloutier, Isabelle Plante, Gervais Bérubé, Carlos Reyes-Moreno
Format: Article
Language:English
Published: MDPI AG 2025-08-01
Series:Molecules
Subjects:
inflammation
luminal breast cancer
macrophages
<i>para</i>-aminobenzoic acid (PABA)
small molecules
triple-negative breast cancer
Online Access:https://www.mdpi.com/1420-3049/30/15/3284
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https://www.mdpi.com/1420-3049/30/15/3284

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