Primary immune deficiency disease awareness among a group of Turkish physicians

Primary immunodeficiencies (PIDs) are a relatively common occurrence in countries where consanguineous marriages are widespread. A principal factor leading to misdiagnosis and ensuing complications can be the lack of knowledge and proper evaluation. The aim of this study was to assess PID awa...

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Main Authors: Mutlu Yüksek, Aydan Ikincioğullari, Figen Doğu, Atilla Elhan, Nazmiye Yüksek, Ismail Reisli, Emel Babacan
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2010-08-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/5017
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author Mutlu Yüksek
Aydan Ikincioğullari
Figen Doğu
Atilla Elhan
Nazmiye Yüksek
Ismail Reisli
Emel Babacan
author_facet Mutlu Yüksek
Aydan Ikincioğullari
Figen Doğu
Atilla Elhan
Nazmiye Yüksek
Ismail Reisli
Emel Babacan
author_sort Mutlu Yüksek
collection DOAJ
description Primary immunodeficiencies (PIDs) are a relatively common occurrence in countries where consanguineous marriages are widespread. A principal factor leading to misdiagnosis and ensuing complications can be the lack of knowledge and proper evaluation. The aim of this study was to assess PID awareness and the identification of diagnostic criteria leading to correct diagnosis. Seven hundred eighty-six questionnaires with 71 items were distributed to physicians attending the 41st National Congress of Pediatrics (2005) and to pediatric residents of two university hospitals from different cities in Turkey. The 217 completed questionnaires revealed that family history (91.2%), consanguineous marriages (87.1%), infant deaths (70.0%), persistent thrush (90.3%), hospitalization for recurrent cellulitis (70.5%), chronic diarrhea due to giardiasis (62.2%), recurrent oral aphthous lesions (58.5%), telangiectasia (82.0%), failure to thrive (78.8%), absence of tonsil tissue (74.7%), oculocutaneous albinism (73.7%), and resistant sinusitis (71.0%) were cited among important indicators of PID. However, neonatal tetany (77.9%), liver abscess (61.3%) and poliomyelitis following oral polio vaccination (51.2%) were not considered as related to PID. Although white blood cell (WBC) and differential were chosen as the preferred initial tests, leukocytosis and lymphopenia were also not judged as related to PID. More comprehensive pre/postgraduate education in PID appears to be necessary for physicians in Turkey.
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publishDate 2010-08-01
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spelling doaj-art-3f5688192d1f44fda1dab35e8539e2642025-08-20T03:01:11ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212010-08-01524Primary immune deficiency disease awareness among a group of Turkish physiciansMutlu Yüksek0Aydan IkincioğullariFigen DoğuAtilla ElhanNazmiye YüksekIsmail ReisliEmel BabacanDepartment of Pediatric Immunology, Ankara University Faculty of Medicine, Ankara, Turkey. Primary immunodeficiencies (PIDs) are a relatively common occurrence in countries where consanguineous marriages are widespread. A principal factor leading to misdiagnosis and ensuing complications can be the lack of knowledge and proper evaluation. The aim of this study was to assess PID awareness and the identification of diagnostic criteria leading to correct diagnosis. Seven hundred eighty-six questionnaires with 71 items were distributed to physicians attending the 41st National Congress of Pediatrics (2005) and to pediatric residents of two university hospitals from different cities in Turkey. The 217 completed questionnaires revealed that family history (91.2%), consanguineous marriages (87.1%), infant deaths (70.0%), persistent thrush (90.3%), hospitalization for recurrent cellulitis (70.5%), chronic diarrhea due to giardiasis (62.2%), recurrent oral aphthous lesions (58.5%), telangiectasia (82.0%), failure to thrive (78.8%), absence of tonsil tissue (74.7%), oculocutaneous albinism (73.7%), and resistant sinusitis (71.0%) were cited among important indicators of PID. However, neonatal tetany (77.9%), liver abscess (61.3%) and poliomyelitis following oral polio vaccination (51.2%) were not considered as related to PID. Although white blood cell (WBC) and differential were chosen as the preferred initial tests, leukocytosis and lymphopenia were also not judged as related to PID. More comprehensive pre/postgraduate education in PID appears to be necessary for physicians in Turkey. https://turkjpediatr.org/article/view/5017
spellingShingle Mutlu Yüksek
Aydan Ikincioğullari
Figen Doğu
Atilla Elhan
Nazmiye Yüksek
Ismail Reisli
Emel Babacan
Primary immune deficiency disease awareness among a group of Turkish physicians
The Turkish Journal of Pediatrics
title Primary immune deficiency disease awareness among a group of Turkish physicians
title_full Primary immune deficiency disease awareness among a group of Turkish physicians
title_fullStr Primary immune deficiency disease awareness among a group of Turkish physicians
title_full_unstemmed Primary immune deficiency disease awareness among a group of Turkish physicians
title_short Primary immune deficiency disease awareness among a group of Turkish physicians
title_sort primary immune deficiency disease awareness among a group of turkish physicians
url https://turkjpediatr.org/article/view/5017
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AT atillaelhan primaryimmunedeficiencydiseaseawarenessamongagroupofturkishphysicians
AT nazmiyeyuksek primaryimmunedeficiencydiseaseawarenessamongagroupofturkishphysicians
AT ismailreisli primaryimmunedeficiencydiseaseawarenessamongagroupofturkishphysicians
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