Long non-coding RNA CAR10 promotes angiogenesis of lung adenocarcinoma by mediating nuclear LDHA to epigenetically regulate VEGFA/C
Abstract Angiogenesis is a significant character of lung adenocarcinoma (LUAD) and is an important reason leading to high mortality rates of LUAD patients. However, the molecular mechanisms of lncRNAs regulating the angiogenesis in LUAD have not been fully elucidated. Here we show lncRNA chromatin-a...
Saved in:
Main Authors: | Xiaolu Ge, Chao Du, Li Fang, Wei Xu, Juanjuan Xiang, Jiheng Liu, Ming Zhou, Yuejun Chen, Ziyao Wang, Zheng Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-025-07452-x |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Activating CD137 Signaling Promotes Sprouting Angiogenesis via Increased VEGFA Secretion and the VEGFR2/Akt/eNOS Pathway
by: Bo Li, et al.
Published: (2020-01-01) -
The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer
by: Wanli Ge, et al.
Published: (2023-01-01) -
VEGFA, MYC, and JUN are abnormally elevated in the synovial tissue of patients with advanced osteoarthritis
by: Genxiang Rong, et al.
Published: (2025-01-01) -
Nuclear Reprogramming in Mouse Primordial Germ Cells: Epigenetic Contribution
by: Massimo De Felici
Published: (2011-01-01) -
LINC00707 Regulates miR-382-5p/VEGFA Pathway to Enhance Cervical Cancer Progression
by: Hua Guo, et al.
Published: (2021-01-01)