The impact of CYP2C9, VKORC1, and CYP4F2 polymorphisms on warfarin dose requirement in Saudi patients

The impact of CYP2C9, VKORC1, and CYP4F2 polymorphisms on warfarin dose requirement in Saudi patients

BackgroundLimited data are available on factors that affect warfarin dose requirement in Saudi patients. Saudis are among the underrepresented ethnic groups in warfarin pharmacogenetics research. The present study investigated the frequency of CYP2C9*2 and*3, CYP4F2 (G1347A) and VKORC1 –1639G&gt...

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Bibliographic Details
Main Authors: Salha Jokhab, Maha M. AlRasheed, Dana Bakheet, Abdulkareem AlMomen, Nouf AlAboud, Farhad Kamali
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
warfarin
CYP2C9
VKORC1
CYP4F2
polymorphisms
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1547142/full
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