Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment
Sporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/9453701 |
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| author | Walter Belda Luiz Felipe Domingues Passero Ana Thereza Stradioto Casolato |
| author_facet | Walter Belda Luiz Felipe Domingues Passero Ana Thereza Stradioto Casolato |
| author_sort | Walter Belda |
| collection | DOAJ |
| description | Sporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed. |
| format | Article |
| id | doaj-art-3f4b75984dfd47a581dedef617d419f6 |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-3f4b75984dfd47a581dedef617d419f62025-02-03T01:27:19ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712021-01-01202110.1155/2021/94537019453701Lymphocutaneous Sporotrichosis Refractory to First-Line TreatmentWalter Belda0Luiz Felipe Domingues Passero1Ana Thereza Stradioto Casolato2Dermatology Department, University of São Paulo, Medical School, Clinics Hospital, São Paulo, BrazilSão Paulo State University (UNESP), Institute of Biosciences, São Vicente, Presidente Prudente, BrazilDermatology Department, University of São Paulo, Medical School, Clinics Hospital, São Paulo, BrazilSporotrichosis is a fungal infection endemic in Latin America and has been attributed to the thermodimorphic fungus of the genus Sporothrix. Transmission to humans occurs during a traumatic injury with soil or organic material; additionally, lesions caused by infected cats play an important role in the epidemiology of the disease. The classic treatment of sporotrichosis is performed with itraconazole or potassium iodide; second-line medications, such as amphotericin B and terbinafine, can alternatively be used in cases of first-line drug failure. In the present study, a patient with lymphocutaneous sporotrichosis in the right upper limb exhibited intolerance to itraconazole and potassium iodide, additionally during the period of use; these drugs did not control skin lesions. In this patient, amphotericin B deoxycholate and its liposomal version were used in this patient; and complete recovery of the lesions was observed.http://dx.doi.org/10.1155/2021/9453701 |
| spellingShingle | Walter Belda Luiz Felipe Domingues Passero Ana Thereza Stradioto Casolato Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment Case Reports in Dermatological Medicine |
| title | Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
| title_full | Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
| title_fullStr | Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
| title_full_unstemmed | Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
| title_short | Lymphocutaneous Sporotrichosis Refractory to First-Line Treatment |
| title_sort | lymphocutaneous sporotrichosis refractory to first line treatment |
| url | http://dx.doi.org/10.1155/2021/9453701 |
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