Tethered Exosomes Containing the Matrix Metalloproteinase MT1‐MMP Contribute to Extracellular Matrix Degradation

ABSTRACT For cancer cells to escape from the primary tumour and metastasize, they must degrade and navigate through the extracellular matrix (ECM). The transmembrane protease MT1‐matrix metalloprotease (MMP) plays a key role in localized matrix degradation, and its overexpression promotes cancer inv...

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Bibliographic Details
Main Authors: Roberta Palmulli, Hannah K. Jackson, James R. Edgar
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of Extracellular Vesicles
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Online Access:https://doi.org/10.1002/jev2.70122
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