Does Hypothyroidism Affect Gastrointestinal Motility?
Background. Gastrointestinal motility and serum thyroid hormone levels are closely related. Our aim was to analyze whether there is a disorder in esophagogastric motor functions as a result of hypothyroidism. Materials and Methods. The study group included 30 females (mean age ± SE 45.17 ± 2.07 year...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2009/529802 |
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| author | Olga Yaylali Suna Kirac Mustafa Yilmaz Fulya Akin Dogangun Yuksel Nese Demirkan Beyza Akdag |
| author_facet | Olga Yaylali Suna Kirac Mustafa Yilmaz Fulya Akin Dogangun Yuksel Nese Demirkan Beyza Akdag |
| author_sort | Olga Yaylali |
| collection | DOAJ |
| description | Background. Gastrointestinal motility and serum thyroid hormone levels are closely related. Our aim was to analyze whether there is a disorder in esophagogastric motor functions as a result of hypothyroidism. Materials and Methods. The study group included 30 females (mean age ± SE 45.17 ± 2.07 years) with primary hypothyroidism and 10 healthy females (mean age ± SE 39.40 ± 3.95 years). All cases underwent esophagogastric endoscopy and scintigraphy. For esophageal scintigraphy, dynamic imaging of esophagus motility protocol, and for gastric emptying scintigraphy, anterior static gastric images were acquired. Results. The mean esophageal transit time (52.56 ± 4.07 sec for patients; 24.30 ± 5.88 sec for controls; P=.02) and gastric emptying time (49.06 ± 4.29 min for the hypothyroid group; 30.4 ± 4.74 min for the control group; P=.01) were markedly increased in cases of hypothyroidism. Conclusion. Hypothyroidism prominently reduces esophageal and gastric motor activity and can cause gastrointestinal dysfunction. |
| format | Article |
| id | doaj-art-3f3621a82b9c4aa291b5d92b78376270 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-3f3621a82b9c4aa291b5d92b783762702025-02-03T06:00:58ZengWileyGastroenterology Research and Practice1687-61211687-630X2009-01-01200910.1155/2009/529802529802Does Hypothyroidism Affect Gastrointestinal Motility?Olga Yaylali0Suna Kirac1Mustafa Yilmaz2Fulya Akin3Dogangun Yuksel4Nese Demirkan5Beyza Akdag6Department of Nuclear Medicine, Faculty of Medicine, Pamukkale University, Doktorlar Caddesi no. 42, Denizli 20100, TurkeyDepartment of Nuclear Medicine, Faculty of Medicine, Pamukkale University, Doktorlar Caddesi no. 42, Denizli 20100, TurkeyDivision of Gastroenterology, Faculty of Medicine, Pamukkale University Hospital, Kınıklı, Denizli 20020, TurkeyDivision of Endocrinology, Faculty of Medicine, Pamukkale University Hospital, Kınıklı, Denizli 20020, TurkeyDepartment of Nuclear Medicine, Faculty of Medicine, Pamukkale University, Doktorlar Caddesi no. 42, Denizli 20100, TurkeyDepartment of Pathology, Faculty of Medicine, Pamukkale University Hospital, Kınıklı, Denizli 20020, TurkeyDepartment of Biostatistics, Faculty of Medicine, Pamukkale University Hospital, Kınıklı, Denizli 20020, TurkeyBackground. Gastrointestinal motility and serum thyroid hormone levels are closely related. Our aim was to analyze whether there is a disorder in esophagogastric motor functions as a result of hypothyroidism. Materials and Methods. The study group included 30 females (mean age ± SE 45.17 ± 2.07 years) with primary hypothyroidism and 10 healthy females (mean age ± SE 39.40 ± 3.95 years). All cases underwent esophagogastric endoscopy and scintigraphy. For esophageal scintigraphy, dynamic imaging of esophagus motility protocol, and for gastric emptying scintigraphy, anterior static gastric images were acquired. Results. The mean esophageal transit time (52.56 ± 4.07 sec for patients; 24.30 ± 5.88 sec for controls; P=.02) and gastric emptying time (49.06 ± 4.29 min for the hypothyroid group; 30.4 ± 4.74 min for the control group; P=.01) were markedly increased in cases of hypothyroidism. Conclusion. Hypothyroidism prominently reduces esophageal and gastric motor activity and can cause gastrointestinal dysfunction.http://dx.doi.org/10.1155/2009/529802 |
| spellingShingle | Olga Yaylali Suna Kirac Mustafa Yilmaz Fulya Akin Dogangun Yuksel Nese Demirkan Beyza Akdag Does Hypothyroidism Affect Gastrointestinal Motility? Gastroenterology Research and Practice |
| title | Does Hypothyroidism Affect Gastrointestinal Motility? |
| title_full | Does Hypothyroidism Affect Gastrointestinal Motility? |
| title_fullStr | Does Hypothyroidism Affect Gastrointestinal Motility? |
| title_full_unstemmed | Does Hypothyroidism Affect Gastrointestinal Motility? |
| title_short | Does Hypothyroidism Affect Gastrointestinal Motility? |
| title_sort | does hypothyroidism affect gastrointestinal motility |
| url | http://dx.doi.org/10.1155/2009/529802 |
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