Update on Gastroesophageal Reflux and Respiratory Disease in Children
Pediatric respiratory diseases have been linked to gastroesophageal reflux disease (GERD), but evidence regarding the association and its potential mechanisms continues to accumulate, and important aspects remain to be determined. Evidence for the association in two common pediatric respiratory diso...
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| Format: | Article |
| Language: | English |
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Wiley
2000-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2000/918745 |
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| _version_ | 1832551389392273408 |
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| author | Susan R Orenstein |
| author_facet | Susan R Orenstein |
| author_sort | Susan R Orenstein |
| collection | DOAJ |
| description | Pediatric respiratory diseases have been linked to gastroesophageal reflux disease (GERD), but evidence regarding the association and its potential mechanisms continues to accumulate, and important aspects remain to be determined. Evidence for the association in two common pediatric respiratory disorders - infantile apnea and asthma in older children - and difficult clinical issues associated with the diagnosis and treatment of these two disorders are reviewed. The provocative embryological and physiological connections between the upper gastrointestinal tract and the respiratory tract, and recent understanding of the compensatory anatomy and physiology that protect the normal individual from respiratory manifestations of GERD are also explored. Dysfunctions of these protections likely underlie the pathophysiology of these disorders. |
| format | Article |
| id | doaj-art-3f2c629b688140bdb390a12d7be38893 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2000-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-3f2c629b688140bdb390a12d7be388932025-02-03T06:01:33ZengWileyCanadian Journal of Gastroenterology0835-79002000-01-0114213113510.1155/2000/918745Update on Gastroesophageal Reflux and Respiratory Disease in ChildrenSusan R Orenstein0Division of Pediatric Gastroenterology, University of Pittsburgh School of Medicine and Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USAPediatric respiratory diseases have been linked to gastroesophageal reflux disease (GERD), but evidence regarding the association and its potential mechanisms continues to accumulate, and important aspects remain to be determined. Evidence for the association in two common pediatric respiratory disorders - infantile apnea and asthma in older children - and difficult clinical issues associated with the diagnosis and treatment of these two disorders are reviewed. The provocative embryological and physiological connections between the upper gastrointestinal tract and the respiratory tract, and recent understanding of the compensatory anatomy and physiology that protect the normal individual from respiratory manifestations of GERD are also explored. Dysfunctions of these protections likely underlie the pathophysiology of these disorders.http://dx.doi.org/10.1155/2000/918745 |
| spellingShingle | Susan R Orenstein Update on Gastroesophageal Reflux and Respiratory Disease in Children Canadian Journal of Gastroenterology |
| title | Update on Gastroesophageal Reflux and Respiratory Disease in Children |
| title_full | Update on Gastroesophageal Reflux and Respiratory Disease in Children |
| title_fullStr | Update on Gastroesophageal Reflux and Respiratory Disease in Children |
| title_full_unstemmed | Update on Gastroesophageal Reflux and Respiratory Disease in Children |
| title_short | Update on Gastroesophageal Reflux and Respiratory Disease in Children |
| title_sort | update on gastroesophageal reflux and respiratory disease in children |
| url | http://dx.doi.org/10.1155/2000/918745 |
| work_keys_str_mv | AT susanrorenstein updateongastroesophagealrefluxandrespiratorydiseaseinchildren |