PI3K/mTOR Signaling Pathway Dual Inhibition for the Management of Neuroinflammation: Novel Insights from In Vitro Models

PI3K/mTOR Signaling Pathway Dual Inhibition for the Management of Neuroinflammation: Novel Insights from In Vitro Models

Neuroinflammatory responses are central to the pathogenesis of neurodegenerative diseases, affecting cells of both neuronal and glial origin that respond to immune-driven inflammatory stimuli. The PI3K/mTOR signaling pathway is essential for the regulation of these neuroinflammatory processes and is...

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Bibliographic Details
Main Authors: Alessio Ardizzone, Sarah Adriana Scuderi, Giovanna Casili, Rossella Basilotta, Emanuela Esposito, Marika Lanza
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomolecules
Subjects:
neuroinflammation
PI3K/mTOR pathway
in vitro models
neurodegeneration
Online Access:https://www.mdpi.com/2218-273X/15/5/677
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