A familial case of Birt–Hogg–Dubé syndrome complicated with lung cancer: a case report and literature review

The Birt–Hogg–Dubé (BHD) syndrome is a rare, autosomal dominant disorder caused by germline mutations in the FLCN gene, which encodes a tumor suppressor protein. The syndrome is characterized by cutaneous fibrofolliculomas, pulmonary cysts, spontaneous pneumothoraces, and renal tumors. We report a r...

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Bibliographic Details
Main Authors: Jingjing Feng, Yunxia Yu, Yi Liu, Yi Ding, Junyi Mu, Rong Jiang, Lokesh Sharma, Zhijun Jie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1581786/full
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