Circulating tsRNAs serve as potential biomarkers for predicting postoperative delirium in elderly patients receiving lower extremity orthopedic surgery

Circulating tsRNAs serve as potential biomarkers for predicting postoperative delirium in elderly patients receiving lower extremity orthopedic surgery

BackgroundPostoperative delirium (POD) is a serious neuropsychiatric complication in elderly surgical patients, yet its pathogenesis remains incompletely understood. Transfer RNA-derived small RNAs (tsRNAs) have emerged as crucial regulators in neurological disorders. We investigated whether specifi...

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Bibliographic Details
Main Authors: Angyang Cao, Rui Zhao, Chunqu Chen, Can Wu, Yiwei Zhang, Changshun Huang, Binbin Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Psychiatry
Subjects:
tsRNA
postoperative delirium (POD)
RT-qPCR
elderly patients
propensity score matching (PSM)
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1522984/full
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