Plasma phosphorylated tau 217 and amyloid‑β 42/40 for amyloid risk in subgroups

Plasma phosphorylated tau 217 and amyloid‑β 42/40 for amyloid risk in subgroups

Abstract Background Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β (Aβ) pathology. Recently, plasma biomarkers, particularly p-tau217, have emerged as promising tools for early diagnosis and risk stratification. In this retrospective study, we evaluated the diagnostic per...

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Main Authors: Heekyoung Kang, Heejin Yoo, Jungah Lee, Soyeon Yoon, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J. Ashton, Theresa A. Day, Sung Hoon Kang, Jihwan Yun, Min Young Chun, Eun Hye Lee, Jun Pyo Kim, Hee Jin Kim, Duk L. Na, Hyemin Jang, Daeun Shin, Sang Won Seo, the K-ROAD study group
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Plasma biomarkers
p-tau217
Aβ42/40
Diagnostic accuracy
Online Access:https://doi.org/10.1186/s13195-025-01826-3
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