Comparing antibiotic treatment at dry-off on one quarter versus all quarters in cows with only one quarter affected with a high somatic cell count or an intramammary infection
The aim of this randomized controlled study was to evaluate, on cows with only one quarter affected at dry-off with an IMI, a high SCC (>200,000 cells/mL), or both, the impact of treating with an antibiotic plus internal teat sealant only the quarter affected (treating unaffected quarters with te...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
|
| Series: | JDS Communications |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666910224001972 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The aim of this randomized controlled study was to evaluate, on cows with only one quarter affected at dry-off with an IMI, a high SCC (>200,000 cells/mL), or both, the impact of treating with an antibiotic plus internal teat sealant only the quarter affected (treating unaffected quarters with teat sealant alone; SelectAB) versus all quarters (AllAB) on subsequent lactation SCC (analyzed as log10 transformed SCC) and IMI (odds of cure [i.e., affected quarter at dry-off but not at calving]; and odds of healthy [i.e., not affected at dry-off and calving]). Ninety-six multiparous cows from 3 research herds were randomly assigned to SelectAB or AllAB. Linear and logistic regression mixed models were used for data analysis. Cows assigned to AllAB had a 0.15 units lower log10 SCC (95% CI = −0.19 to −0.11 log points) through the full subsequent lactation compared with SelectAB cows. The odds of cure for an affected quarter were similar for AllAB and SelectAB cows (odds ratio = 0.77; 95% CI = 0.27–2.20), but cows under AllAB had higher odds of having a healthy quarter shortly after calving compared with SelectAB cows (odds ratio = 2.86; 95% CI = 1.21–6.73). In conclusion, a reduced rate of healthy quarters (i.e., increased new infections any time from dry-off to shortly after calving), especially in quarters treated with internal teat sealant alone within an udder with one quarter affected with IMI, high SCC, or both at dry-off, may be a major barrier for the implementation of a quarter-based dry-off treatment approach. |
|---|---|
| ISSN: | 2666-9102 |