Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook)
The present work was to evaluate the anti-inflammatory activity of Delonix regia leaves (Family: Caesalpiniaceae). The powder of Delonix regia leaves was subjected to extraction with ethanol in soxhlet extractor. The ethanol extract after preliminary phytochemical investigation showed the presence o...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Advances in Pharmacological Sciences |
| Online Access: | http://dx.doi.org/10.1155/2012/789713 |
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| author | Vaishali D. Shewale Tushar A. Deshmukh Liladhar S. Patil Vijay R. Patil |
| author_facet | Vaishali D. Shewale Tushar A. Deshmukh Liladhar S. Patil Vijay R. Patil |
| author_sort | Vaishali D. Shewale |
| collection | DOAJ |
| description | The present work was to evaluate the anti-inflammatory activity of Delonix regia leaves (Family: Caesalpiniaceae). The powder of Delonix regia leaves was subjected to extraction with ethanol in soxhlet extractor. The ethanol extract after preliminary phytochemical investigation showed the presence of sterols, triterpenoids, phenolic compounds and flavonoids. The anti-inflammatory activity was studied using carrageenan-induced rat paw edema and cotton pellet granuloma at a three different doses (100, 200, and 400 mg/kg b.w. p.o.) of ethanol extract. The ethanol extract of Delonix regia leaves was exhibited significant anti-inflammatory activity at the dose of 400 mg/kg in both models when compared with control group. Indomethacin (10 mg/kg b.w. p.o) was also shown significant anti-inflammatory activity in both models. |
| format | Article |
| id | doaj-art-3f06d53ea15d48a1a8539e0f53d3f94d |
| institution | Kabale University |
| issn | 1687-6334 1687-6342 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Pharmacological Sciences |
| spelling | doaj-art-3f06d53ea15d48a1a8539e0f53d3f94d2025-08-20T03:35:53ZengWileyAdvances in Pharmacological Sciences1687-63341687-63422012-01-01201210.1155/2012/789713789713Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook)Vaishali D. Shewale0Tushar A. Deshmukh1Liladhar S. Patil2Vijay R. Patil3Tapi Valley Education Society, Hon’ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, IndiaTapi Valley Education Society, Hon’ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, IndiaTapi Valley Education Society, Hon’ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, IndiaTapi Valley Education Society, Hon’ble, Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur 425 503, IndiaThe present work was to evaluate the anti-inflammatory activity of Delonix regia leaves (Family: Caesalpiniaceae). The powder of Delonix regia leaves was subjected to extraction with ethanol in soxhlet extractor. The ethanol extract after preliminary phytochemical investigation showed the presence of sterols, triterpenoids, phenolic compounds and flavonoids. The anti-inflammatory activity was studied using carrageenan-induced rat paw edema and cotton pellet granuloma at a three different doses (100, 200, and 400 mg/kg b.w. p.o.) of ethanol extract. The ethanol extract of Delonix regia leaves was exhibited significant anti-inflammatory activity at the dose of 400 mg/kg in both models when compared with control group. Indomethacin (10 mg/kg b.w. p.o) was also shown significant anti-inflammatory activity in both models.http://dx.doi.org/10.1155/2012/789713 |
| spellingShingle | Vaishali D. Shewale Tushar A. Deshmukh Liladhar S. Patil Vijay R. Patil Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook) Advances in Pharmacological Sciences |
| title | Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook) |
| title_full | Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook) |
| title_fullStr | Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook) |
| title_full_unstemmed | Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook) |
| title_short | Anti-Inflammatory Activity of Delonix regia (Boj. Ex. Hook) |
| title_sort | anti inflammatory activity of delonix regia boj ex hook |
| url | http://dx.doi.org/10.1155/2012/789713 |
| work_keys_str_mv | AT vaishalidshewale antiinflammatoryactivityofdelonixregiabojexhook AT tusharadeshmukh antiinflammatoryactivityofdelonixregiabojexhook AT liladharspatil antiinflammatoryactivityofdelonixregiabojexhook AT vijayrpatil antiinflammatoryactivityofdelonixregiabojexhook |