Pulmonary Mucormycosis in a Patient with Systemic Lupus Erythematosus: A Diagnostic and Treatment Challenge
Pulmonary mucormycosis is commonly encountered in patients with diabetic ketoacidosis, hematologic malignancies, neutropenia, organ or hematopoietic stem cell transplantation, and malignancy, but it rarely occurs in high-risk patients with systemic lupus erythematosus (SLE). We present the case of a...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2015/478789 |
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| author | Hung-Chang Hung Gang-Yu Shen Shiuan-Chih Chen Kai-Jieh Yeo Shih-Ming Tsao Meng-Chih Lee Yuan-Ti Lee |
| author_facet | Hung-Chang Hung Gang-Yu Shen Shiuan-Chih Chen Kai-Jieh Yeo Shih-Ming Tsao Meng-Chih Lee Yuan-Ti Lee |
| author_sort | Hung-Chang Hung |
| collection | DOAJ |
| description | Pulmonary mucormycosis is commonly encountered in patients with diabetic ketoacidosis, hematologic malignancies, neutropenia, organ or hematopoietic stem cell transplantation, and malignancy, but it rarely occurs in high-risk patients with systemic lupus erythematosus (SLE). We present the case of a 40-year-old SLE female with fulminant pneumonia after remission of nephritis treated with rituximab, who developed severe pulmonary mucormycosis that led to her rapid death from acute respiratory failure and acute respiratory distress syndrome. Pulmonary mucormycosis has a high mortality rate. However, with early diagnosis and antifungal therapy with lipid formulation-liposomal amphotericin B and surgical removal of the infected area, the outcome can be improved. |
| format | Article |
| id | doaj-art-3f00a730688d4ee79faba447a7894564 |
| institution | OA Journals |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-3f00a730688d4ee79faba447a78945642025-08-20T02:08:07ZengWileyCase Reports in Infectious Diseases2090-66252090-66332015-01-01201510.1155/2015/478789478789Pulmonary Mucormycosis in a Patient with Systemic Lupus Erythematosus: A Diagnostic and Treatment ChallengeHung-Chang Hung0Gang-Yu Shen1Shiuan-Chih Chen2Kai-Jieh Yeo3Shih-Ming Tsao4Meng-Chih Lee5Yuan-Ti Lee6Division of Gastroenterology, Department of Internal Medicine, Nantou Hospital, Ministry of Health and Welfare, No. 478, Fuxing Road, Nantou City, Nantou County 540, TaiwanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chiu General Hospital, No. 137, Chenggong First Road, Lingya District, Kaohsiung 802, TaiwanDepartment of Family and Community Medicine, Chung Shan Medical University Hospital, No. 110, Section 1, Jianguo North Road, Taichung 402, TaiwanSchool of Medicine, Chung Shan Medical University, No. 110, Section 1, Jianguo North Road, Taichung 402, TaiwanSchool of Medicine, Chung Shan Medical University, No. 110, Section 1, Jianguo North Road, Taichung 402, TaiwanDepartment of Family and Community Medicine, Chung Shan Medical University Hospital, No. 110, Section 1, Jianguo North Road, Taichung 402, TaiwanSchool of Medicine, Chung Shan Medical University, No. 110, Section 1, Jianguo North Road, Taichung 402, TaiwanPulmonary mucormycosis is commonly encountered in patients with diabetic ketoacidosis, hematologic malignancies, neutropenia, organ or hematopoietic stem cell transplantation, and malignancy, but it rarely occurs in high-risk patients with systemic lupus erythematosus (SLE). We present the case of a 40-year-old SLE female with fulminant pneumonia after remission of nephritis treated with rituximab, who developed severe pulmonary mucormycosis that led to her rapid death from acute respiratory failure and acute respiratory distress syndrome. Pulmonary mucormycosis has a high mortality rate. However, with early diagnosis and antifungal therapy with lipid formulation-liposomal amphotericin B and surgical removal of the infected area, the outcome can be improved.http://dx.doi.org/10.1155/2015/478789 |
| spellingShingle | Hung-Chang Hung Gang-Yu Shen Shiuan-Chih Chen Kai-Jieh Yeo Shih-Ming Tsao Meng-Chih Lee Yuan-Ti Lee Pulmonary Mucormycosis in a Patient with Systemic Lupus Erythematosus: A Diagnostic and Treatment Challenge Case Reports in Infectious Diseases |
| title | Pulmonary Mucormycosis in a Patient with Systemic Lupus Erythematosus: A Diagnostic and Treatment Challenge |
| title_full | Pulmonary Mucormycosis in a Patient with Systemic Lupus Erythematosus: A Diagnostic and Treatment Challenge |
| title_fullStr | Pulmonary Mucormycosis in a Patient with Systemic Lupus Erythematosus: A Diagnostic and Treatment Challenge |
| title_full_unstemmed | Pulmonary Mucormycosis in a Patient with Systemic Lupus Erythematosus: A Diagnostic and Treatment Challenge |
| title_short | Pulmonary Mucormycosis in a Patient with Systemic Lupus Erythematosus: A Diagnostic and Treatment Challenge |
| title_sort | pulmonary mucormycosis in a patient with systemic lupus erythematosus a diagnostic and treatment challenge |
| url | http://dx.doi.org/10.1155/2015/478789 |
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