Current Status of Diagnosis and Treatment of High-risk Resistant and Recurrent Gestational Trophoblastic Neoplasia
Gestational trophoblastic neoplasia (GTN) patients can be classified into low-risk and high-risk patients based on the International Federation of Gynecology and Obstetrics(FIGO) staging and scoring system. High-risk patients have a higher risk of resistance to single-agent chemotherapy and require...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Medical Journal of Peking Union Medical College Hospital
2024-04-01
|
| Series: | Xiehe Yixue Zazhi |
| Subjects: | |
| Online Access: | https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0135 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1823865220425056256 |
|---|---|
| author | MAO Mingyi JIANG Fang XIANG Yang |
| author_facet | MAO Mingyi JIANG Fang XIANG Yang |
| author_sort | MAO Mingyi |
| collection | DOAJ |
| description | Gestational trophoblastic neoplasia (GTN) patients can be classified into low-risk and high-risk patients based on the International Federation of Gynecology and Obstetrics(FIGO) staging and scoring system. High-risk patients have a higher risk of resistance to single-agent chemotherapy and require combination chemotherapy. Even worse, there are some high-risk patients who develop resistance to combination chemotherapy or experience recurrence after cure. These patients exhibit strong heterogeneity and pose significant challenges to subsequent treatment, thus attracting considerable attention in recent years. Therefore, this article aims to review the risk factors and treatment strategies for high-risk resistant and recurrent GTN patients, in order to provide a basis for early identification of high-risk patients and their precise treatment. |
| format | Article |
| id | doaj-art-3ef503ef6c184bddba671bbbbd7a87dc |
| institution | Kabale University |
| issn | 1674-9081 |
| language | zho |
| publishDate | 2024-04-01 |
| publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
| record_format | Article |
| series | Xiehe Yixue Zazhi |
| spelling | doaj-art-3ef503ef6c184bddba671bbbbd7a87dc2025-02-08T07:47:34ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812024-04-0116115716210.12290/xhyxzz.2024-0135Current Status of Diagnosis and Treatment of High-risk Resistant and Recurrent Gestational Trophoblastic NeoplasiaMAO MingyiJIANG Fang0XIANG Yang1National Clinical Research Center for Obstetric & Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaNational Clinical Research Center for Obstetric & Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaGestational trophoblastic neoplasia (GTN) patients can be classified into low-risk and high-risk patients based on the International Federation of Gynecology and Obstetrics(FIGO) staging and scoring system. High-risk patients have a higher risk of resistance to single-agent chemotherapy and require combination chemotherapy. Even worse, there are some high-risk patients who develop resistance to combination chemotherapy or experience recurrence after cure. These patients exhibit strong heterogeneity and pose significant challenges to subsequent treatment, thus attracting considerable attention in recent years. Therefore, this article aims to review the risk factors and treatment strategies for high-risk resistant and recurrent GTN patients, in order to provide a basis for early identification of high-risk patients and their precise treatment.https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0135gestational trophoblastic neoplasiahigh-riskresistancerecurrence |
| spellingShingle | MAO Mingyi JIANG Fang XIANG Yang Current Status of Diagnosis and Treatment of High-risk Resistant and Recurrent Gestational Trophoblastic Neoplasia Xiehe Yixue Zazhi gestational trophoblastic neoplasia high-risk resistance recurrence |
| title | Current Status of Diagnosis and Treatment of High-risk Resistant and Recurrent Gestational Trophoblastic Neoplasia |
| title_full | Current Status of Diagnosis and Treatment of High-risk Resistant and Recurrent Gestational Trophoblastic Neoplasia |
| title_fullStr | Current Status of Diagnosis and Treatment of High-risk Resistant and Recurrent Gestational Trophoblastic Neoplasia |
| title_full_unstemmed | Current Status of Diagnosis and Treatment of High-risk Resistant and Recurrent Gestational Trophoblastic Neoplasia |
| title_short | Current Status of Diagnosis and Treatment of High-risk Resistant and Recurrent Gestational Trophoblastic Neoplasia |
| title_sort | current status of diagnosis and treatment of high risk resistant and recurrent gestational trophoblastic neoplasia |
| topic | gestational trophoblastic neoplasia high-risk resistance recurrence |
| url | https://xhyxzz.pumch.cn/article/doi/10.12290/xhyxzz.2024-0135 |
| work_keys_str_mv | AT maomingyi currentstatusofdiagnosisandtreatmentofhighriskresistantandrecurrentgestationaltrophoblasticneoplasia AT jiangfang currentstatusofdiagnosisandtreatmentofhighriskresistantandrecurrentgestationaltrophoblasticneoplasia AT xiangyang currentstatusofdiagnosisandtreatmentofhighriskresistantandrecurrentgestationaltrophoblasticneoplasia |