Synchronous Occurrence of Collagenous and Pseudomembranous Colitis
Synchronous collagenous and pseudomembranous colitis has not been previously reported. A 73-year-old woman presented with chronic watery diarrhea and abdominal cramping of six weeks’ duration. Biopsies of the colon revealed findings of collagenous colitis involving the endoscopically normal right co...
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| Format: | Article |
| Language: | English |
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Wiley
2000-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2000/350453 |
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| author | Z Vesoulis G Lozanski T Loiudice |
| author_facet | Z Vesoulis G Lozanski T Loiudice |
| author_sort | Z Vesoulis |
| collection | DOAJ |
| description | Synchronous collagenous and pseudomembranous colitis has not been previously reported. A 73-year-old woman presented with chronic watery diarrhea and abdominal cramping of six weeks’ duration. Biopsies of the colon revealed findings of collagenous colitis involving the endoscopically normal right colon, and superimposed collagenous and pseudomembranous colitis involving the rectosigmoid colon. Endoscopically, the left colon revealed discrete ulcerative plaques, and Clostridium difficile toxin A assay was positive. The patient partially responded to a three-week regimen of metronidazole, and symptoms resolved completely with subsequent steroid therapy. At follow-up endoscopy four months later, colon biopsies demonstrated persistence of subepithelial collagen but no pseudomembranes. The patient remained asymptomatic during this interval. Collagenous colitis has been reported in association with other inflammatory bowel diseases, including lymphocytic colitis, sprue and idiopathic inflammatory bowel disease. This unique association of collagenous colitis with an endotoxigenic inflammatory bowel disease is presented with a review of related disease features. |
| format | Article |
| id | doaj-art-3ee951d8cf6b4ad692fa43e971d8bf70 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2000-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-3ee951d8cf6b4ad692fa43e971d8bf702025-02-03T01:32:48ZengWileyCanadian Journal of Gastroenterology0835-79002000-01-0114435335810.1155/2000/350453Synchronous Occurrence of Collagenous and Pseudomembranous ColitisZ Vesoulis0G Lozanski1T Loiudice2Department of Pathology, Summa Health System, Akron, Ohio, USADepartment of Pathology, Summa Health System, Akron, Ohio, USADepartment of Internal Medicine, Summa Health System, Akron, Ohio, USASynchronous collagenous and pseudomembranous colitis has not been previously reported. A 73-year-old woman presented with chronic watery diarrhea and abdominal cramping of six weeks’ duration. Biopsies of the colon revealed findings of collagenous colitis involving the endoscopically normal right colon, and superimposed collagenous and pseudomembranous colitis involving the rectosigmoid colon. Endoscopically, the left colon revealed discrete ulcerative plaques, and Clostridium difficile toxin A assay was positive. The patient partially responded to a three-week regimen of metronidazole, and symptoms resolved completely with subsequent steroid therapy. At follow-up endoscopy four months later, colon biopsies demonstrated persistence of subepithelial collagen but no pseudomembranes. The patient remained asymptomatic during this interval. Collagenous colitis has been reported in association with other inflammatory bowel diseases, including lymphocytic colitis, sprue and idiopathic inflammatory bowel disease. This unique association of collagenous colitis with an endotoxigenic inflammatory bowel disease is presented with a review of related disease features.http://dx.doi.org/10.1155/2000/350453 |
| spellingShingle | Z Vesoulis G Lozanski T Loiudice Synchronous Occurrence of Collagenous and Pseudomembranous Colitis Canadian Journal of Gastroenterology |
| title | Synchronous Occurrence of Collagenous and Pseudomembranous Colitis |
| title_full | Synchronous Occurrence of Collagenous and Pseudomembranous Colitis |
| title_fullStr | Synchronous Occurrence of Collagenous and Pseudomembranous Colitis |
| title_full_unstemmed | Synchronous Occurrence of Collagenous and Pseudomembranous Colitis |
| title_short | Synchronous Occurrence of Collagenous and Pseudomembranous Colitis |
| title_sort | synchronous occurrence of collagenous and pseudomembranous colitis |
| url | http://dx.doi.org/10.1155/2000/350453 |
| work_keys_str_mv | AT zvesoulis synchronousoccurrenceofcollagenousandpseudomembranouscolitis AT glozanski synchronousoccurrenceofcollagenousandpseudomembranouscolitis AT tloiudice synchronousoccurrenceofcollagenousandpseudomembranouscolitis |