Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms

Bullous pemphigoid (BP) is a chronic autoimmune skin disease. It is characterized by the presence of well-tense blisters in the area of erythematous-oedematous eruptions, as well as in the unaffected skin that often develops lesions triggered by medications or focal points. The treatment involves th...

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Main Authors: Przemysław Borowy, Olga Wcisłek, Julia Płonczyńska, Mateusz Heba, Bogdan Batko
Format: Article
Language:English
Published: Termedia Publishing House 2025-01-01
Series:Przegląd Dermatologiczny
Subjects:
Online Access:https://www.termedia.pl/Bullous-pemphigoid-as-a-diagnostic-and-therapeutic-challenge-with-a-wide-spectrum-of-dermatological-symptoms,56,55448,1,1.html
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author Przemysław Borowy
Olga Wcisłek
Julia Płonczyńska
Mateusz Heba
Bogdan Batko
author_facet Przemysław Borowy
Olga Wcisłek
Julia Płonczyńska
Mateusz Heba
Bogdan Batko
author_sort Przemysław Borowy
collection DOAJ
description Bullous pemphigoid (BP) is a chronic autoimmune skin disease. It is characterized by the presence of well-tense blisters in the area of erythematous-oedematous eruptions, as well as in the unaffected skin that often develops lesions triggered by medications or focal points. The treatment involves the use of topical or systemic glucocorticosteroids (GCS) and, in challenging cases, immunosuppressive drugs. In a 74-year-old patient with internistic and psychiatric burdens, and oral lesions present for the several past months. BP was diagnosed in surgical biopsies based on immunohistopathological results and specific antibody detection. The case presents diagnostic challenges and various forms of topical therapy in a patient with multiple diseases responsible for limited access to recommended drugs.
format Article
id doaj-art-3ecc2a7e1d6c4232b740dad4256ef34b
institution Kabale University
issn 0033-2526
2084-9893
language English
publishDate 2025-01-01
publisher Termedia Publishing House
record_format Article
series Przegląd Dermatologiczny
spelling doaj-art-3ecc2a7e1d6c4232b740dad4256ef34b2025-01-27T11:10:28ZengTermedia Publishing HousePrzegląd Dermatologiczny0033-25262084-98932025-01-01111429529810.5114/dr.2024.14662855448Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptomsPrzemysław BorowyOlga WcisłekJulia PłonczyńskaMateusz HebaBogdan BatkoBullous pemphigoid (BP) is a chronic autoimmune skin disease. It is characterized by the presence of well-tense blisters in the area of erythematous-oedematous eruptions, as well as in the unaffected skin that often develops lesions triggered by medications or focal points. The treatment involves the use of topical or systemic glucocorticosteroids (GCS) and, in challenging cases, immunosuppressive drugs. In a 74-year-old patient with internistic and psychiatric burdens, and oral lesions present for the several past months. BP was diagnosed in surgical biopsies based on immunohistopathological results and specific antibody detection. The case presents diagnostic challenges and various forms of topical therapy in a patient with multiple diseases responsible for limited access to recommended drugs.https://www.termedia.pl/Bullous-pemphigoid-as-a-diagnostic-and-therapeutic-challenge-with-a-wide-spectrum-of-dermatological-symptoms,56,55448,1,1.htmltreatment glucocorticosteroids oral ulcers bullous pemphigoid
spellingShingle Przemysław Borowy
Olga Wcisłek
Julia Płonczyńska
Mateusz Heba
Bogdan Batko
Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms
Przegląd Dermatologiczny
treatment
glucocorticosteroids
oral ulcers
bullous pemphigoid
title Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms
title_full Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms
title_fullStr Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms
title_full_unstemmed Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms
title_short Bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms
title_sort bullous pemphigoid as a diagnostic and therapeutic challenge with a wide spectrum of dermatological symptoms
topic treatment
glucocorticosteroids
oral ulcers
bullous pemphigoid
url https://www.termedia.pl/Bullous-pemphigoid-as-a-diagnostic-and-therapeutic-challenge-with-a-wide-spectrum-of-dermatological-symptoms,56,55448,1,1.html
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AT juliapłonczynska bullouspemphigoidasadiagnosticandtherapeuticchallengewithawidespectrumofdermatologicalsymptoms
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