Etiopathogenetic Similarities of Combined Forms of Localized Scleroderma and Vitiligo
Vitiligo is a common skin disease characterized by idiopathic progressive skin hypomelanosis. Vitiligo is associated with several comorbid autoimmune diseases such as localized scleroderma. This article demonstrates the general development mechanism of these pathologies, as well as the key aspect of...
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2020-12-01
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| Series: | Вопросы современной педиатрии |
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| Online Access: | https://vsp.spr-journal.ru/jour/article/view/2506 |
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| author | Nikolay N. Murashkin Alena A. Savelova Roman A. Ivanov Eduard T. Ambarchian Alexander I. Materikin Roman V. Epishev Leonid A. Opryatin |
| author_facet | Nikolay N. Murashkin Alena A. Savelova Roman A. Ivanov Eduard T. Ambarchian Alexander I. Materikin Roman V. Epishev Leonid A. Opryatin |
| author_sort | Nikolay N. Murashkin |
| collection | DOAJ |
| description | Vitiligo is a common skin disease characterized by idiopathic progressive skin hypomelanosis. Vitiligo is associated with several comorbid autoimmune diseases such as localized scleroderma. This article demonstrates the general development mechanism of these pathologies, as well as the key aspect of cross-effect between autoimmune diseases on the molecular level. Recently, dermatologists have noted the increasing number of patients suffering from combined pathologies. Such patients (in pediatrics) have torpid course of disease and no pathognomonic symptoms. That exaggerates the diagnostics and adequate therapy prescription. This leads to increased awareness among physicians of different specialties on possible combinations, clinical presentation and pathogenesis aspects of such conditions. |
| format | Article |
| id | doaj-art-3ec653d377a34c32982e0e85a8f73030 |
| institution | Kabale University |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-3ec653d377a34c32982e0e85a8f730302025-08-20T03:59:53Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352020-12-0119645245910.15690/vsp.v19i6.21471914Etiopathogenetic Similarities of Combined Forms of Localized Scleroderma and VitiligoNikolay N. Murashkin0Alena A. Savelova1Roman A. Ivanov2Eduard T. Ambarchian3Alexander I. Materikin4Roman V. Epishev5Leonid A. Opryatin6National Medical Research Center of Children’s Health; Sechenov First Moscow State Medical University (Sechenov University); Central State Medical Academy of Department of Presidential Affairs; Research Institute of Pediatrics and Children’s Health in “Central Clinical Hospital of the Russian Academy of Sciences”Central State Medical Academy of Department of Presidential AffairsNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthVitiligo is a common skin disease characterized by idiopathic progressive skin hypomelanosis. Vitiligo is associated with several comorbid autoimmune diseases such as localized scleroderma. This article demonstrates the general development mechanism of these pathologies, as well as the key aspect of cross-effect between autoimmune diseases on the molecular level. Recently, dermatologists have noted the increasing number of patients suffering from combined pathologies. Such patients (in pediatrics) have torpid course of disease and no pathognomonic symptoms. That exaggerates the diagnostics and adequate therapy prescription. This leads to increased awareness among physicians of different specialties on possible combinations, clinical presentation and pathogenesis aspects of such conditions.https://vsp.spr-journal.ru/jour/article/view/2506vitiligolocalized sclerodermamelanocyteswntshha-smamosaicism“en coup de saber” |
| spellingShingle | Nikolay N. Murashkin Alena A. Savelova Roman A. Ivanov Eduard T. Ambarchian Alexander I. Materikin Roman V. Epishev Leonid A. Opryatin Etiopathogenetic Similarities of Combined Forms of Localized Scleroderma and Vitiligo Вопросы современной педиатрии vitiligo localized scleroderma melanocytes wnt shh a-sma mosaicism “en coup de saber” |
| title | Etiopathogenetic Similarities of Combined Forms of Localized Scleroderma and Vitiligo |
| title_full | Etiopathogenetic Similarities of Combined Forms of Localized Scleroderma and Vitiligo |
| title_fullStr | Etiopathogenetic Similarities of Combined Forms of Localized Scleroderma and Vitiligo |
| title_full_unstemmed | Etiopathogenetic Similarities of Combined Forms of Localized Scleroderma and Vitiligo |
| title_short | Etiopathogenetic Similarities of Combined Forms of Localized Scleroderma and Vitiligo |
| title_sort | etiopathogenetic similarities of combined forms of localized scleroderma and vitiligo |
| topic | vitiligo localized scleroderma melanocytes wnt shh a-sma mosaicism “en coup de saber” |
| url | https://vsp.spr-journal.ru/jour/article/view/2506 |
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