A comparative study to know the effect of ropivacaine 0.5% and a mixture of bupivacaine 0.5% and lidocaine 2% on intraocular pressure following peribulbar block in cataract operation

PURPOSE: The purpose of this study was to evaluate the effectiveness of ropivacaine 0.5% and the combination of bupivacaine 0.5% and lidocaine 2% on intraocular pressure (IOP) before and after the peribulbar anesthesia in cataract operation and to know the ideal drug with minimal complications. METH...

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Main Authors: Rekha Ramesh Mudhol, Lingamaneni Sneha
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:BLDE University Journal of Health Sciences
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Online Access:https://journals.lww.com/10.4103/bjhs.bjhs_7_25
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author Rekha Ramesh Mudhol
Lingamaneni Sneha
author_facet Rekha Ramesh Mudhol
Lingamaneni Sneha
author_sort Rekha Ramesh Mudhol
collection DOAJ
description PURPOSE: The purpose of this study was to evaluate the effectiveness of ropivacaine 0.5% and the combination of bupivacaine 0.5% and lidocaine 2% on intraocular pressure (IOP) before and after the peribulbar anesthesia in cataract operation and to know the ideal drug with minimal complications. METHODS: A double-blinded, randomized study was done on 62 patients with cataracts planned for cataract operation under regional anesthesia who were allotted to Group 1 and Group 2: 0.5% ropivacaine was given to Group 1 and 0.5% bupivacaine and 2% lidocaine mixture were given to Group 2. A detailed eye examination was done. Peribulbar block with 8 ml of the drug, given in the inferotemporal quadrant, and IOP was measured with a rebound tonometer (iCare IC100) preblock and postblock at 1, 5, and 15 min. Postblock akinesia, pain, surgical satisfaction, and motor recovery scorings were done. P value was deemed statistically significant if it was below 0.05. RESULTS: 63.32 ± 7.167 was the mean age of patients in Group 1 and 60.39 ± 9.807 in Group 2. The postblock increase in IOP was seen in both groups, with the ropivacaine group (Group 1) having a significantly lower rise than Group 2. However, IOP returned to normal at the end of 15 min in Group 1 and Group 2. Akinesia, surgical satisfaction, and motor recovery showed significant results, and none of the patients reported pain. CONCLUSION: Based on the study’s findings, we can say that low-concentrated ropivacaine is a viable substitute for the most often-used combination of lidocaine and bupivacaine for a peribulbar block during cataract operation. To demonstrate the advantage of this low-concentrated ropivacaine over the other most commonly used medications in the peribulbar block, more research with a larger sample size and 0.5% ropivacaine is needed.
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spelling doaj-art-3ec2229fb9d240149c53b955fecbd6fe2025-08-20T03:29:28ZengWolters Kluwer Medknow PublicationsBLDE University Journal of Health Sciences2468-838X2456-19752025-01-01101465110.4103/bjhs.bjhs_7_25A comparative study to know the effect of ropivacaine 0.5% and a mixture of bupivacaine 0.5% and lidocaine 2% on intraocular pressure following peribulbar block in cataract operationRekha Ramesh MudholLingamaneni SnehaPURPOSE: The purpose of this study was to evaluate the effectiveness of ropivacaine 0.5% and the combination of bupivacaine 0.5% and lidocaine 2% on intraocular pressure (IOP) before and after the peribulbar anesthesia in cataract operation and to know the ideal drug with minimal complications. METHODS: A double-blinded, randomized study was done on 62 patients with cataracts planned for cataract operation under regional anesthesia who were allotted to Group 1 and Group 2: 0.5% ropivacaine was given to Group 1 and 0.5% bupivacaine and 2% lidocaine mixture were given to Group 2. A detailed eye examination was done. Peribulbar block with 8 ml of the drug, given in the inferotemporal quadrant, and IOP was measured with a rebound tonometer (iCare IC100) preblock and postblock at 1, 5, and 15 min. Postblock akinesia, pain, surgical satisfaction, and motor recovery scorings were done. P value was deemed statistically significant if it was below 0.05. RESULTS: 63.32 ± 7.167 was the mean age of patients in Group 1 and 60.39 ± 9.807 in Group 2. The postblock increase in IOP was seen in both groups, with the ropivacaine group (Group 1) having a significantly lower rise than Group 2. However, IOP returned to normal at the end of 15 min in Group 1 and Group 2. Akinesia, surgical satisfaction, and motor recovery showed significant results, and none of the patients reported pain. CONCLUSION: Based on the study’s findings, we can say that low-concentrated ropivacaine is a viable substitute for the most often-used combination of lidocaine and bupivacaine for a peribulbar block during cataract operation. To demonstrate the advantage of this low-concentrated ropivacaine over the other most commonly used medications in the peribulbar block, more research with a larger sample size and 0.5% ropivacaine is needed.https://journals.lww.com/10.4103/bjhs.bjhs_7_250.5% ropivacainebupivacaineintraocular pressurelidocaineperibulbar block
spellingShingle Rekha Ramesh Mudhol
Lingamaneni Sneha
A comparative study to know the effect of ropivacaine 0.5% and a mixture of bupivacaine 0.5% and lidocaine 2% on intraocular pressure following peribulbar block in cataract operation
BLDE University Journal of Health Sciences
0.5% ropivacaine
bupivacaine
intraocular pressure
lidocaine
peribulbar block
title A comparative study to know the effect of ropivacaine 0.5% and a mixture of bupivacaine 0.5% and lidocaine 2% on intraocular pressure following peribulbar block in cataract operation
title_full A comparative study to know the effect of ropivacaine 0.5% and a mixture of bupivacaine 0.5% and lidocaine 2% on intraocular pressure following peribulbar block in cataract operation
title_fullStr A comparative study to know the effect of ropivacaine 0.5% and a mixture of bupivacaine 0.5% and lidocaine 2% on intraocular pressure following peribulbar block in cataract operation
title_full_unstemmed A comparative study to know the effect of ropivacaine 0.5% and a mixture of bupivacaine 0.5% and lidocaine 2% on intraocular pressure following peribulbar block in cataract operation
title_short A comparative study to know the effect of ropivacaine 0.5% and a mixture of bupivacaine 0.5% and lidocaine 2% on intraocular pressure following peribulbar block in cataract operation
title_sort comparative study to know the effect of ropivacaine 0 5 and a mixture of bupivacaine 0 5 and lidocaine 2 on intraocular pressure following peribulbar block in cataract operation
topic 0.5% ropivacaine
bupivacaine
intraocular pressure
lidocaine
peribulbar block
url https://journals.lww.com/10.4103/bjhs.bjhs_7_25
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