Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis
Background. Periampullary tumors (PT) may rarely present as acute pancreatitis (AP) or acute recurrent pancreatitis (ARP). Unlike other cases of AP and ARP, these conditions necessitate pancreaticoduodenectomy (PD), and timely diagnosis is crucial. Materials and Methods. A retrospective review of cl...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/7246895 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832555103548080128 |
|---|---|
| author | Xuefeng Cao Xixiu Wang Xiaoliang Xu Yanmin Lu Baolei Zhao Xingyuan Zhang Qiangpu Chen |
| author_facet | Xuefeng Cao Xixiu Wang Xiaoliang Xu Yanmin Lu Baolei Zhao Xingyuan Zhang Qiangpu Chen |
| author_sort | Xuefeng Cao |
| collection | DOAJ |
| description | Background. Periampullary tumors (PT) may rarely present as acute pancreatitis (AP) or acute recurrent pancreatitis (ARP). Unlike other cases of AP and ARP, these conditions necessitate pancreaticoduodenectomy (PD), and timely diagnosis is crucial. Materials and Methods. A retrospective review of clinical, radiological, surgical, and pathological data was conducted for patients admitted to the Binzhou Medical University Hospital during the period from January 2010 to December 2017, for AP or ARP caused by PT. All patients included in the study group had undergone PD. The perioperative data for these patients was compared with data for patients with PT but without AP or ARP who underwent PD during the same period (control group). Results. During the study period, 412 patients with AP or ARP were treated; among this group, 15 patients had PT. Compared with controls, patients in the study group were younger in age and had a longer course of disease, more frequent hospitalizations, and more severe derangements in laboratory data (P<0.05). Operative time and intraoperative blood loss were significantly higher in the study group, but the incidence of postoperative outcomes such as pancreatic/biliary fistula, abdominal infection, postoperative hospital stay, and mortality were similar between groups (P>0.05). Conclusions. Neither AP nor ARP has any adverse impact on the outcomes of PD. However, in the treatment of younger patients suffering from AP or ARP, unexplained pancreatic duct dilation and weight loss should raise the suspicion of PT. EUS and EUS-FNA may be helpful in making the diagnosis. |
| format | Article |
| id | doaj-art-3ebde286cf1b44e6ad7f5ddfa5ae4a7c |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-3ebde286cf1b44e6ad7f5ddfa5ae4a7c2025-02-03T05:49:30ZengWileyGastroenterology Research and Practice1687-61211687-630X2020-01-01202010.1155/2020/72468957246895Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute PancreatitisXuefeng Cao0Xixiu Wang1Xiaoliang Xu2Yanmin Lu3Baolei Zhao4Xingyuan Zhang5Qiangpu Chen6Department of Hepatobiliary Surgery, Binzhou Medical University Hospital, Binzhou, Shandong Province, ChinaDepartment of Cardiovascular Medicine, Binzhou Medical University Hospital, Binzhou, Shandong Province, ChinaPediatric Surgery, Binzhou Medical University Hospital, Binzhou, Shandong Province, ChinaNutriology Department, Binzhou Medical University Hospital, Binzhou, Shandong Province, ChinaDepartment of Hepatobiliary Surgery, Binzhou Medical University Hospital, Binzhou, Shandong Province, ChinaDepartment of Hepatobiliary Surgery, Binzhou Medical University Hospital, Binzhou, Shandong Province, ChinaDepartment of Hepatobiliary Surgery, Binzhou Medical University Hospital, Binzhou, Shandong Province, ChinaBackground. Periampullary tumors (PT) may rarely present as acute pancreatitis (AP) or acute recurrent pancreatitis (ARP). Unlike other cases of AP and ARP, these conditions necessitate pancreaticoduodenectomy (PD), and timely diagnosis is crucial. Materials and Methods. A retrospective review of clinical, radiological, surgical, and pathological data was conducted for patients admitted to the Binzhou Medical University Hospital during the period from January 2010 to December 2017, for AP or ARP caused by PT. All patients included in the study group had undergone PD. The perioperative data for these patients was compared with data for patients with PT but without AP or ARP who underwent PD during the same period (control group). Results. During the study period, 412 patients with AP or ARP were treated; among this group, 15 patients had PT. Compared with controls, patients in the study group were younger in age and had a longer course of disease, more frequent hospitalizations, and more severe derangements in laboratory data (P<0.05). Operative time and intraoperative blood loss were significantly higher in the study group, but the incidence of postoperative outcomes such as pancreatic/biliary fistula, abdominal infection, postoperative hospital stay, and mortality were similar between groups (P>0.05). Conclusions. Neither AP nor ARP has any adverse impact on the outcomes of PD. However, in the treatment of younger patients suffering from AP or ARP, unexplained pancreatic duct dilation and weight loss should raise the suspicion of PT. EUS and EUS-FNA may be helpful in making the diagnosis.http://dx.doi.org/10.1155/2020/7246895 |
| spellingShingle | Xuefeng Cao Xixiu Wang Xiaoliang Xu Yanmin Lu Baolei Zhao Xingyuan Zhang Qiangpu Chen Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis Gastroenterology Research and Practice |
| title | Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis |
| title_full | Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis |
| title_fullStr | Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis |
| title_full_unstemmed | Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis |
| title_short | Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis |
| title_sort | pancreatoduodenectomy for periampullary tumors presenting with acute pancreatitis |
| url | http://dx.doi.org/10.1155/2020/7246895 |
| work_keys_str_mv | AT xuefengcao pancreatoduodenectomyforperiampullarytumorspresentingwithacutepancreatitis AT xixiuwang pancreatoduodenectomyforperiampullarytumorspresentingwithacutepancreatitis AT xiaoliangxu pancreatoduodenectomyforperiampullarytumorspresentingwithacutepancreatitis AT yanminlu pancreatoduodenectomyforperiampullarytumorspresentingwithacutepancreatitis AT baoleizhao pancreatoduodenectomyforperiampullarytumorspresentingwithacutepancreatitis AT xingyuanzhang pancreatoduodenectomyforperiampullarytumorspresentingwithacutepancreatitis AT qiangpuchen pancreatoduodenectomyforperiampullarytumorspresentingwithacutepancreatitis |