Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota Diversity
Cardiovascular diseases (CVDs), which comprise coronary heart disease, hypertension, and stroke, collectively represent the number one cause of death globally. Atherosclerosis is the dominant cause of CVDs, and its risk factors are elevated levels of low-density lipoprotein cholesterol and triglycer...
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MDPI AG
2024-11-01
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| Series: | Marine Drugs |
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| Online Access: | https://www.mdpi.com/1660-3397/22/11/523 |
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| author | Ingrid Lamminpää Amedeo Amedei Cinzia Parolini |
| author_facet | Ingrid Lamminpää Amedeo Amedei Cinzia Parolini |
| author_sort | Ingrid Lamminpää |
| collection | DOAJ |
| description | Cardiovascular diseases (CVDs), which comprise coronary heart disease, hypertension, and stroke, collectively represent the number one cause of death globally. Atherosclerosis is the dominant cause of CVDs, and its risk factors are elevated levels of low-density lipoprotein cholesterol and triglycerides, hypertension, cigarette smoking, obesity, and diabetes mellitus. In addition, diverse evidence highlights the role played by inflammation and clonal haematopoiesis, eventually leading to immunity involvement. The human microbiota project and subsequent studies using next-generation sequencing technology have indicated that thousands of different microbial species are present in the human gut. Disturbances in the gut microbiota (GM) composition, i.e., gut dysbiosis, have been associated with diseases ranging from localised gastrointestinal disorders to metabolic and cardiovascular illnesses. Of note, experimental studies suggested that GM, host immune cells, and marine-derived ingredients work together to ensure intestinal wall integrity. This review discusses current evidence concerning the links among GM, marine-derived ingredients, and human inflammatory disease. In detail, we summarise the impact of fish-derived proteins/peptides and algae components on CVD risk factors and gut microbiome. Furthermore, we describe the interplay among these dietary components, probiotics/prebiotics, and CVDs. |
| format | Article |
| id | doaj-art-3eb803fe8b5d47a6a5a5f309397ce67c |
| institution | DOAJ |
| issn | 1660-3397 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj-art-3eb803fe8b5d47a6a5a5f309397ce67c2025-08-20T02:48:05ZengMDPI AGMarine Drugs1660-33972024-11-01221152310.3390/md22110523Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota DiversityIngrid Lamminpää0Amedeo Amedei1Cinzia Parolini2Department of Clinical and Experimental Medicine, University of Florence, 50134 Florence, ItalyDepartment of Clinical and Experimental Medicine, University of Florence, 50134 Florence, ItalyDepartment of Pharmacological and Biomolecular Sciences, ‘Rodolfo Paoletti’, Via Balzaretti 9, Università degli Studi di Milano, 20133 Milano, ItalyCardiovascular diseases (CVDs), which comprise coronary heart disease, hypertension, and stroke, collectively represent the number one cause of death globally. Atherosclerosis is the dominant cause of CVDs, and its risk factors are elevated levels of low-density lipoprotein cholesterol and triglycerides, hypertension, cigarette smoking, obesity, and diabetes mellitus. In addition, diverse evidence highlights the role played by inflammation and clonal haematopoiesis, eventually leading to immunity involvement. The human microbiota project and subsequent studies using next-generation sequencing technology have indicated that thousands of different microbial species are present in the human gut. Disturbances in the gut microbiota (GM) composition, i.e., gut dysbiosis, have been associated with diseases ranging from localised gastrointestinal disorders to metabolic and cardiovascular illnesses. Of note, experimental studies suggested that GM, host immune cells, and marine-derived ingredients work together to ensure intestinal wall integrity. This review discusses current evidence concerning the links among GM, marine-derived ingredients, and human inflammatory disease. In detail, we summarise the impact of fish-derived proteins/peptides and algae components on CVD risk factors and gut microbiome. Furthermore, we describe the interplay among these dietary components, probiotics/prebiotics, and CVDs.https://www.mdpi.com/1660-3397/22/11/523cardiovascular diseasesatherosclerosis risk factorsmicrobiotafish protein hydrolysatesseaweedsmarine-derived ingredients |
| spellingShingle | Ingrid Lamminpää Amedeo Amedei Cinzia Parolini Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota Diversity Marine Drugs cardiovascular diseases atherosclerosis risk factors microbiota fish protein hydrolysates seaweeds marine-derived ingredients |
| title | Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota Diversity |
| title_full | Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota Diversity |
| title_fullStr | Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota Diversity |
| title_full_unstemmed | Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota Diversity |
| title_short | Effects of Marine-Derived Components on Cardiovascular Disease Risk Factors and Gut Microbiota Diversity |
| title_sort | effects of marine derived components on cardiovascular disease risk factors and gut microbiota diversity |
| topic | cardiovascular diseases atherosclerosis risk factors microbiota fish protein hydrolysates seaweeds marine-derived ingredients |
| url | https://www.mdpi.com/1660-3397/22/11/523 |
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