Tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bonding

Abstract Radicals from tooth whitening products can reduce bond strength, posing challenges for dentists when a bonding procedure must be performed in teeth immediately after whitening. This study aimed to evaluate the antioxidant activity (AA) of Terminalia catappa Linn (TCL) leaf extract as a pote...

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Main Authors: Verónica Cecilia MEJÍA, Vitória Moraes MARQUES, Tamara Gonçalves de ARAÚJO, Lara Cecília de MOURA, Ana Cristina de Mello FIALLOS, Mary Anne Sampaio de MELO, Sérgio Lima SANTIAGO, Vanara Florêncio PASSOS
Format: Article
Language:English
Published: Sociedade Brasileira de Pesquisa Odontológica 2025-06-01
Series:Brazilian Oral Research
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242025000100455&lng=en&tlng=en
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author Verónica Cecilia MEJÍA
Vitória Moraes MARQUES
Tamara Gonçalves de ARAÚJO
Lara Cecília de MOURA
Ana Cristina de Mello FIALLOS
Mary Anne Sampaio de MELO
Sérgio Lima SANTIAGO
Vanara Florêncio PASSOS
author_facet Verónica Cecilia MEJÍA
Vitória Moraes MARQUES
Tamara Gonçalves de ARAÚJO
Lara Cecília de MOURA
Ana Cristina de Mello FIALLOS
Mary Anne Sampaio de MELO
Sérgio Lima SANTIAGO
Vanara Florêncio PASSOS
author_sort Verónica Cecilia MEJÍA
collection DOAJ
description Abstract Radicals from tooth whitening products can reduce bond strength, posing challenges for dentists when a bonding procedure must be performed in teeth immediately after whitening. This study aimed to evaluate the antioxidant activity (AA) of Terminalia catappa Linn (TCL) leaf extract as a potential agent to mitigate the negative impact of high-concentration whitening agents on immediate bonding performance. The AA of green and ripe leaf extracts was measured using the 2,2-di-phenyl-1-picrylhydrazyl radical scavenging capacity assay (DPPH). To determine the TCL influence on bond strength, six groups of bovine enamel blocks (n=10) were created. Group 1 was the positive control (unbleached enamel), while Group 2 was the negative control (no antioxidant treatment). Groups 3 to 6 were bleached and treated with 10% sodium ascorbate (SA) or 0.1%, 0.2%, and 0.3% TCL gels. Adhesion was conducted using a two-step conventional system and dental composite resin. Microtensile testing was performed after 24 hours, and data were analyzed by one-way ANOVA with Tukey’s post hoc test (p > 0.05). From the DPPH assay, results with IC50 < 50 µg/mL indicate high AA for all tested extracts. This method established a difference of around 12 times more AA for the TCL-hydroalcoholic extract of green leaf to the aqueous extract of ripe leaves. There were no significant differences in bond strength among groups treated with TCL-hydroalcoholic extract of green leaf gels (p > 0.05) and unbleached enamel. Tropical almond-derived antioxidant gels emerge as a promising strategy to enhance immediate bond strength on enamel after high-concentration in-office whitening treatments.
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publishDate 2025-06-01
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record_format Article
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spelling doaj-art-3eb4c5bf346a4c92b00d175b84c75f9b2025-08-20T03:28:17ZengSociedade Brasileira de Pesquisa OdontológicaBrazilian Oral Research1807-31072025-06-013910.1590/1807-3107bor-2025.vol39.072Tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bondingVerónica Cecilia MEJÍAhttps://orcid.org/0009-0001-9095-0899Vitória Moraes MARQUEShttps://orcid.org/0009-0003-3250-7914Tamara Gonçalves de ARAÚJOhttps://orcid.org/0000-0002-1360-479XLara Cecília de MOURAhttps://orcid.org/0009-0004-2823-632XAna Cristina de Mello FIALLOShttps://orcid.org/0000-0003-2227-809XMary Anne Sampaio de MELOhttps://orcid.org/0000-0002-0007-2966Sérgio Lima SANTIAGOhttps://orcid.org/0000-0002-6808-092XVanara Florêncio PASSOShttps://orcid.org/0000-0001-5121-0436Abstract Radicals from tooth whitening products can reduce bond strength, posing challenges for dentists when a bonding procedure must be performed in teeth immediately after whitening. This study aimed to evaluate the antioxidant activity (AA) of Terminalia catappa Linn (TCL) leaf extract as a potential agent to mitigate the negative impact of high-concentration whitening agents on immediate bonding performance. The AA of green and ripe leaf extracts was measured using the 2,2-di-phenyl-1-picrylhydrazyl radical scavenging capacity assay (DPPH). To determine the TCL influence on bond strength, six groups of bovine enamel blocks (n=10) were created. Group 1 was the positive control (unbleached enamel), while Group 2 was the negative control (no antioxidant treatment). Groups 3 to 6 were bleached and treated with 10% sodium ascorbate (SA) or 0.1%, 0.2%, and 0.3% TCL gels. Adhesion was conducted using a two-step conventional system and dental composite resin. Microtensile testing was performed after 24 hours, and data were analyzed by one-way ANOVA with Tukey’s post hoc test (p > 0.05). From the DPPH assay, results with IC50 < 50 µg/mL indicate high AA for all tested extracts. This method established a difference of around 12 times more AA for the TCL-hydroalcoholic extract of green leaf to the aqueous extract of ripe leaves. There were no significant differences in bond strength among groups treated with TCL-hydroalcoholic extract of green leaf gels (p > 0.05) and unbleached enamel. Tropical almond-derived antioxidant gels emerge as a promising strategy to enhance immediate bond strength on enamel after high-concentration in-office whitening treatments.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242025000100455&lng=en&tlng=enReactive Oxygen SpeciesHydrogen PeroxideAscorbic AcidDental CementsDental AdhesivesDental Enamel
spellingShingle Verónica Cecilia MEJÍA
Vitória Moraes MARQUES
Tamara Gonçalves de ARAÚJO
Lara Cecília de MOURA
Ana Cristina de Mello FIALLOS
Mary Anne Sampaio de MELO
Sérgio Lima SANTIAGO
Vanara Florêncio PASSOS
Tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bonding
Brazilian Oral Research
Reactive Oxygen Species
Hydrogen Peroxide
Ascorbic Acid
Dental Cements
Dental Adhesives
Dental Enamel
title Tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bonding
title_full Tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bonding
title_fullStr Tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bonding
title_full_unstemmed Tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bonding
title_short Tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bonding
title_sort tropical almond antioxidant gels mitigate the adverse effects of strong whitening agents on immediate bonding
topic Reactive Oxygen Species
Hydrogen Peroxide
Ascorbic Acid
Dental Cements
Dental Adhesives
Dental Enamel
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242025000100455&lng=en&tlng=en
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