COMPARATIVE EFFECTIVENESS OF THE COMBINATIONS OF DIURETICS AND DIHYDROPYRIDINE AND NONDIHYDROPYRIDINE CALCIUM ANTAGONISTS IN PATIENTS WITH ARTERIAL HYPERTENSION

In total, 54 patients, aged 42-65 years, with Stage II arterial hypertension (AH) were examined. At baseline and 16 weeks after the treatment phase, 24-hour blood pressure monitoring (BPM) and Doppler echocardiography were performed. The patients were randomised into 2 groups: Group 1 received combi...

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Main Authors: B. G. Iskenderov, E. V. Gridneva, O. N. Sisina, L. F. Burmistrova, S. V. Saushkina
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2010-12-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/1512
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author B. G. Iskenderov
E. V. Gridneva
O. N. Sisina
L. F. Burmistrova
S. V. Saushkina
author_facet B. G. Iskenderov
E. V. Gridneva
O. N. Sisina
L. F. Burmistrova
S. V. Saushkina
author_sort B. G. Iskenderov
collection DOAJ
description In total, 54 patients, aged 42-65 years, with Stage II arterial hypertension (AH) were examined. At baseline and 16 weeks after the treatment phase, 24-hour blood pressure monitoring (BPM) and Doppler echocardiography were performed. The patients were randomised into 2 groups: Group 1 received combined therapy with indapamide and verapamil retard, while Group 2 was administered indapamide and amlodipine. Circadian BP rhythm was normalised in 82,8% and 76,0% of the patients from Groups 1 and 2, respectively. In Group 1, combined therapy was more effective among patients with Type I left ventricular diastolic dysfunction (LVDD), non-dipper circadian BP profile, and hyperkinetic circulation type. In Group 2, the therapy was more effective among participants with Type II-III LVDD and hypokinetic circulation type.
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id doaj-art-3eaea6b3e9d243df909a4ba74d952f01
institution DOAJ
issn 1560-4071
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language Russian
publishDate 2010-12-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-3eaea6b3e9d243df909a4ba74d952f012025-08-20T03:21:54Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202010-12-010634391299COMPARATIVE EFFECTIVENESS OF THE COMBINATIONS OF DIURETICS AND DIHYDROPYRIDINE AND NONDIHYDROPYRIDINE CALCIUM ANTAGONISTS IN PATIENTS WITH ARTERIAL HYPERTENSIONB. G. Iskenderov0E. V. Gridneva1O. N. Sisina2L. F. Burmistrova3S. V. Saushkina4Пензенский медицинский институт, ПензаПензенский медицинский институт, ПензаПензенский медицинский институт, ПензаПензенский институт усовершенствования врачейПензенский медицинский институт, ПензаIn total, 54 patients, aged 42-65 years, with Stage II arterial hypertension (AH) were examined. At baseline and 16 weeks after the treatment phase, 24-hour blood pressure monitoring (BPM) and Doppler echocardiography were performed. The patients were randomised into 2 groups: Group 1 received combined therapy with indapamide and verapamil retard, while Group 2 was administered indapamide and amlodipine. Circadian BP rhythm was normalised in 82,8% and 76,0% of the patients from Groups 1 and 2, respectively. In Group 1, combined therapy was more effective among patients with Type I left ventricular diastolic dysfunction (LVDD), non-dipper circadian BP profile, and hyperkinetic circulation type. In Group 2, the therapy was more effective among participants with Type II-III LVDD and hypokinetic circulation type.https://russjcardiol.elpub.ru/jour/article/view/1512arterial hypertensioncombined therapyindapamideverapamil retardamlodipine
spellingShingle B. G. Iskenderov
E. V. Gridneva
O. N. Sisina
L. F. Burmistrova
S. V. Saushkina
COMPARATIVE EFFECTIVENESS OF THE COMBINATIONS OF DIURETICS AND DIHYDROPYRIDINE AND NONDIHYDROPYRIDINE CALCIUM ANTAGONISTS IN PATIENTS WITH ARTERIAL HYPERTENSION
Российский кардиологический журнал
arterial hypertension
combined therapy
indapamide
verapamil retard
amlodipine
title COMPARATIVE EFFECTIVENESS OF THE COMBINATIONS OF DIURETICS AND DIHYDROPYRIDINE AND NONDIHYDROPYRIDINE CALCIUM ANTAGONISTS IN PATIENTS WITH ARTERIAL HYPERTENSION
title_full COMPARATIVE EFFECTIVENESS OF THE COMBINATIONS OF DIURETICS AND DIHYDROPYRIDINE AND NONDIHYDROPYRIDINE CALCIUM ANTAGONISTS IN PATIENTS WITH ARTERIAL HYPERTENSION
title_fullStr COMPARATIVE EFFECTIVENESS OF THE COMBINATIONS OF DIURETICS AND DIHYDROPYRIDINE AND NONDIHYDROPYRIDINE CALCIUM ANTAGONISTS IN PATIENTS WITH ARTERIAL HYPERTENSION
title_full_unstemmed COMPARATIVE EFFECTIVENESS OF THE COMBINATIONS OF DIURETICS AND DIHYDROPYRIDINE AND NONDIHYDROPYRIDINE CALCIUM ANTAGONISTS IN PATIENTS WITH ARTERIAL HYPERTENSION
title_short COMPARATIVE EFFECTIVENESS OF THE COMBINATIONS OF DIURETICS AND DIHYDROPYRIDINE AND NONDIHYDROPYRIDINE CALCIUM ANTAGONISTS IN PATIENTS WITH ARTERIAL HYPERTENSION
title_sort comparative effectiveness of the combinations of diuretics and dihydropyridine and nondihydropyridine calcium antagonists in patients with arterial hypertension
topic arterial hypertension
combined therapy
indapamide
verapamil retard
amlodipine
url https://russjcardiol.elpub.ru/jour/article/view/1512
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AT evgridneva comparativeeffectivenessofthecombinationsofdiureticsanddihydropyridineandnondihydropyridinecalciumantagonistsinpatientswitharterialhypertension
AT onsisina comparativeeffectivenessofthecombinationsofdiureticsanddihydropyridineandnondihydropyridinecalciumantagonistsinpatientswitharterialhypertension
AT lfburmistrova comparativeeffectivenessofthecombinationsofdiureticsanddihydropyridineandnondihydropyridinecalciumantagonistsinpatientswitharterialhypertension
AT svsaushkina comparativeeffectivenessofthecombinationsofdiureticsanddihydropyridineandnondihydropyridinecalciumantagonistsinpatientswitharterialhypertension