Biosynthesis of L-Lysine-a-Oxidase, an Antitumor Enzyme, by Trichoderma spp
Strains of Trichoderma spp., producing L-lysine-a-oxidase, prospective in chemotherapy of malignant tumors, were studied. The best results of the enzyme biosynthesis were observed on the wheat bran medium. When grown on the media with various pH levels, the strains showed different spectra of the L-...
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| Format: | Article |
| Language: | Russian |
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LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
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| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/229 |
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| author | I. P. Smirnova S. B. Alekseev A. A. Shevchenko |
| author_facet | I. P. Smirnova S. B. Alekseev A. A. Shevchenko |
| author_sort | I. P. Smirnova |
| collection | DOAJ |
| description | Strains of Trichoderma spp., producing L-lysine-a-oxidase, prospective in chemotherapy of malignant tumors, were studied. The best results of the enzyme biosynthesis were observed on the wheat bran medium. When grown on the media with various pH levels, the strains showed different spectra of the L-aminooxidase activity. The highest activity of the strains was recorded with respect to destruction of L-lysine. The lysine-producing organism Brevibacterium sp. induced L-lysine-a-oxidase activity in Trichoderma spp. |
| format | Article |
| id | doaj-art-3ead5663bc1f4a9c94f1da4a648d2aa1 |
| institution | DOAJ |
| issn | 0235-2990 |
| language | Russian |
| publishDate | 2020-05-01 |
| publisher | LLC "Publishing House OKI" |
| record_format | Article |
| series | Антибиотики и Химиотерапия |
| spelling | doaj-art-3ead5663bc1f4a9c94f1da4a648d2aa12025-08-20T02:49:35ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01545-6812228Biosynthesis of L-Lysine-a-Oxidase, an Antitumor Enzyme, by Trichoderma sppI. P. Smirnova0S. B. Alekseev1A. A. Shevchenko2Russian University of Peaples' Friendship, MoscowRussian University of Peaples' Friendship, MoscowRussian University of Peaples' Friendship, MoscowStrains of Trichoderma spp., producing L-lysine-a-oxidase, prospective in chemotherapy of malignant tumors, were studied. The best results of the enzyme biosynthesis were observed on the wheat bran medium. When grown on the media with various pH levels, the strains showed different spectra of the L-aminooxidase activity. The highest activity of the strains was recorded with respect to destruction of L-lysine. The lysine-producing organism Brevibacterium sp. induced L-lysine-a-oxidase activity in Trichoderma spp.https://www.antibiotics-chemotherapy.ru/jour/article/view/229trichoderma sppl-лизин-а-оксидазаtrichoderma sppbiosynthesisl-lysine-a-oxidase |
| spellingShingle | I. P. Smirnova S. B. Alekseev A. A. Shevchenko Biosynthesis of L-Lysine-a-Oxidase, an Antitumor Enzyme, by Trichoderma spp Антибиотики и Химиотерапия trichoderma spp l-лизин-а-оксидаза trichoderma spp biosynthesis l-lysine-a-oxidase |
| title | Biosynthesis of L-Lysine-a-Oxidase, an Antitumor Enzyme, by Trichoderma spp |
| title_full | Biosynthesis of L-Lysine-a-Oxidase, an Antitumor Enzyme, by Trichoderma spp |
| title_fullStr | Biosynthesis of L-Lysine-a-Oxidase, an Antitumor Enzyme, by Trichoderma spp |
| title_full_unstemmed | Biosynthesis of L-Lysine-a-Oxidase, an Antitumor Enzyme, by Trichoderma spp |
| title_short | Biosynthesis of L-Lysine-a-Oxidase, an Antitumor Enzyme, by Trichoderma spp |
| title_sort | biosynthesis of l lysine a oxidase an antitumor enzyme by trichoderma spp |
| topic | trichoderma spp l-лизин-а-оксидаза trichoderma spp biosynthesis l-lysine-a-oxidase |
| url | https://www.antibiotics-chemotherapy.ru/jour/article/view/229 |
| work_keys_str_mv | AT ipsmirnova biosynthesisofllysineaoxidaseanantitumorenzymebytrichodermaspp AT sbalekseev biosynthesisofllysineaoxidaseanantitumorenzymebytrichodermaspp AT aashevchenko biosynthesisofllysineaoxidaseanantitumorenzymebytrichodermaspp |