Effects of testosterone undecanoate treatment on serum biochemical parameters in new zealand rabbits
<b>Aim: </b>Anabolic androgenic steroids (AAS), used to treat various diseases, are also doping substances for athletes to improve their sportive performance. The aim of this study is to evaluate some serum biochemical parameters in New Zealand rabbits treated with long-term Testosterone...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Selcuk University Press
2024-06-01
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| Series: | Eurasian Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=1450 |
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| Summary: | <b>Aim: </b>Anabolic androgenic steroids (AAS), used to treat various diseases, are
also doping substances for athletes to improve their sportive performance.
The aim of this study is to evaluate some serum biochemical parameters in
New Zealand rabbits treated with long-term Testosterone Undecanoate (TU).<p>
<b>Materials and Methods: </b>In the present study, 21 male New Zealand rabbits
aged 5-6 weeks were divided into 3 groups; control, castor oil group, and TU
group (in which TU was diluted in castor oil). In the Castor oil and TU diluted
in castor oil (10 mg/kg) were injected intramuscularly in 0.1 ml for 6 weeks,
5 days a week in the related groups.<p>
<b>Results:</b> The results of the study, in which a total of 22 biochemical
parameters were evaluated, showed that aspartate aminotransferase,
amylase, triglyceride, total cholesterol, total protein, creatinine, uric acid,
phosphate, potassium, sodium, calcium, and glucose levels were statistically
significantly higher in the TU group than in the control and castor oil groups,
and high-density lipoprotein levels were significantly lower in the other
groups compared to the control group.<p>
<b>Conclusion:</b> In conclusion, it can be stated that TU administration
may adversely affect serum biochemistry in New Zealand rabbits and
multidisciplinary studies with different testosterone analogues should be
performed. |
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| ISSN: | 1309-6958 2146-1953 |