Environmental Antimicrobial Resistance: Implications for Food Safety and Public Health

Antimicrobial resistance (AMR) is a serious global health issue, aggravated by antibiotic overuse and misuse in human medicine, animal care, and agriculture. This study looks at the different mechanisms that drive AMR, such as environmental contamination, horizontal gene transfer, and selective pres...

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Main Authors: Onyinye Victoria Ifedinezi, Nnabueze Darlington Nnaji, Christian Kosisochukwu Anumudu, Chiemerie Theresa Ekwueme, Chijioke Christopher Uhegwu, Francis Chukwuebuka Ihenetu, Promiselynda Obioha, Blessing Oteta Simon, Precious Somtochukwu Ezechukwu, Helen Onyeaka
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Antibiotics
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Online Access:https://www.mdpi.com/2079-6382/13/11/1087
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author Onyinye Victoria Ifedinezi
Nnabueze Darlington Nnaji
Christian Kosisochukwu Anumudu
Chiemerie Theresa Ekwueme
Chijioke Christopher Uhegwu
Francis Chukwuebuka Ihenetu
Promiselynda Obioha
Blessing Oteta Simon
Precious Somtochukwu Ezechukwu
Helen Onyeaka
author_facet Onyinye Victoria Ifedinezi
Nnabueze Darlington Nnaji
Christian Kosisochukwu Anumudu
Chiemerie Theresa Ekwueme
Chijioke Christopher Uhegwu
Francis Chukwuebuka Ihenetu
Promiselynda Obioha
Blessing Oteta Simon
Precious Somtochukwu Ezechukwu
Helen Onyeaka
author_sort Onyinye Victoria Ifedinezi
collection DOAJ
description Antimicrobial resistance (AMR) is a serious global health issue, aggravated by antibiotic overuse and misuse in human medicine, animal care, and agriculture. This study looks at the different mechanisms that drive AMR, such as environmental contamination, horizontal gene transfer, and selective pressure, as well as the severe implications of AMR for human and animal health. This study demonstrates the need for concerted efforts across the scientific, healthcare, agricultural, and policy sectors to control the emergence of AMR. Some crucial strategies discussed include developing antimicrobial stewardship (AMS) programs, encouraging targeted narrow-spectrum antibiotic use, and emphasizing the significance of strict regulatory frameworks and surveillance systems, like the Global Antimicrobial Resistance and Use Surveillance System (GLASS) and the Access, Watch, and Reserve (AWaRe) classification. This study also emphasizes the need for national and international action plans in combating AMR and promotes the One Health strategy, which unifies environmental, animal, and human health. This study concludes that preventing the spread of AMR and maintaining the effectiveness of antibiotics for future generations requires a comprehensive, multidisciplinary, and internationally coordinated strategy.
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series Antibiotics
spelling doaj-art-3e9b74f03d8b41b0a300098ea88399702025-08-20T02:26:47ZengMDPI AGAntibiotics2079-63822024-11-011311108710.3390/antibiotics13111087Environmental Antimicrobial Resistance: Implications for Food Safety and Public HealthOnyinye Victoria Ifedinezi0Nnabueze Darlington Nnaji1Christian Kosisochukwu Anumudu2Chiemerie Theresa Ekwueme3Chijioke Christopher Uhegwu4Francis Chukwuebuka Ihenetu5Promiselynda Obioha6Blessing Oteta Simon7Precious Somtochukwu Ezechukwu8Helen Onyeaka9Department of Pharmaceutical Chemistry, University of South Wales, Newport NP20 2BP, UKSchool of Chemical Engineering, University of Birmingham, Birmingham B15 2TT, UKSchool of Chemical Engineering, University of Birmingham, Birmingham B15 2TT, UKSchool of Health and Life Sciences, Teesside University, Middlesbrough TS1 3BX, UKDepartment of Microbiology, Federal University Otuoke, Otuoke 562103, NigeriaDepartment of Microbiology, Imo State University, Owerri 460222, NigeriaMicrobiology Research Unit, School of Human Sciences, London Metropolitan University, 166-220 Holloway Road, London N7 8DB, UKDepartment of Public Health Sciences, National Open University of Nigeria, Abuja 900108, NigeriaSchool of Molecular Bioscience, University of Glasgow, Glasgow G12 8QQ, UKSchool of Chemical Engineering, University of Birmingham, Birmingham B15 2TT, UKAntimicrobial resistance (AMR) is a serious global health issue, aggravated by antibiotic overuse and misuse in human medicine, animal care, and agriculture. This study looks at the different mechanisms that drive AMR, such as environmental contamination, horizontal gene transfer, and selective pressure, as well as the severe implications of AMR for human and animal health. This study demonstrates the need for concerted efforts across the scientific, healthcare, agricultural, and policy sectors to control the emergence of AMR. Some crucial strategies discussed include developing antimicrobial stewardship (AMS) programs, encouraging targeted narrow-spectrum antibiotic use, and emphasizing the significance of strict regulatory frameworks and surveillance systems, like the Global Antimicrobial Resistance and Use Surveillance System (GLASS) and the Access, Watch, and Reserve (AWaRe) classification. This study also emphasizes the need for national and international action plans in combating AMR and promotes the One Health strategy, which unifies environmental, animal, and human health. This study concludes that preventing the spread of AMR and maintaining the effectiveness of antibiotics for future generations requires a comprehensive, multidisciplinary, and internationally coordinated strategy.https://www.mdpi.com/2079-6382/13/11/1087antimicrobial resistanceOne Health approachantibiotic stewardshipsurveillance systemspublic healthanimal husbandry
spellingShingle Onyinye Victoria Ifedinezi
Nnabueze Darlington Nnaji
Christian Kosisochukwu Anumudu
Chiemerie Theresa Ekwueme
Chijioke Christopher Uhegwu
Francis Chukwuebuka Ihenetu
Promiselynda Obioha
Blessing Oteta Simon
Precious Somtochukwu Ezechukwu
Helen Onyeaka
Environmental Antimicrobial Resistance: Implications for Food Safety and Public Health
Antibiotics
antimicrobial resistance
One Health approach
antibiotic stewardship
surveillance systems
public health
animal husbandry
title Environmental Antimicrobial Resistance: Implications for Food Safety and Public Health
title_full Environmental Antimicrobial Resistance: Implications for Food Safety and Public Health
title_fullStr Environmental Antimicrobial Resistance: Implications for Food Safety and Public Health
title_full_unstemmed Environmental Antimicrobial Resistance: Implications for Food Safety and Public Health
title_short Environmental Antimicrobial Resistance: Implications for Food Safety and Public Health
title_sort environmental antimicrobial resistance implications for food safety and public health
topic antimicrobial resistance
One Health approach
antibiotic stewardship
surveillance systems
public health
animal husbandry
url https://www.mdpi.com/2079-6382/13/11/1087
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