Quantification of trace 227Ac and other radionuclidic impurities in mass-separated 225Ac samples produced at CERN-MEDICIS

Quantification of trace 227Ac and other radionuclidic impurities in mass-separated 225Ac samples produced at CERN-MEDICIS

Abstract 225Ac is a promising candidate medical radionuclide for targeted alpha therapy of advanced stage cancers. One of the main production pathways is the high-energy proton spallation of thorium-based targets, that requires an efficient, nuclide-selective separation method to recover 225Ac from...

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Main Authors: Jake D. Johnson, Cyril Bernerd, Frank Bruchertseifer, Thomas E. Cocolios, Marie Deseyn, Charlotte Duchemin, Michael Heines, Max Keppens, Laura Lambert, Nathan Meurrens, Ralf E. Rossel, Thierry Stora, Viktor Van den Bergh
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-02277-4
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