Acute Leukoencephalopathy with Diffusion Restriction in a Toddler
We report a case of acute leukoencephalopathy with restricted diffusion (ALERD) in a 2½-year-old male who presented with fever, seizures, and altered sensorium. Cerebrospinal fluid showed lymphocytic pleocytosis, whereas brain magnetic resonance imaging revealed T2 hyperintensities with restricted d...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-07-01
|
| Series: | Current Medical Issues |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/cmi.cmi_6_25 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850038069560868864 |
|---|---|
| author | Siva Vyasam Jyothi Jayaram Naga Anudeep Mylavarapu Anuj Guleria Siddharth Khanna Renu Suthar Suresh Kumar Angurana |
| author_facet | Siva Vyasam Jyothi Jayaram Naga Anudeep Mylavarapu Anuj Guleria Siddharth Khanna Renu Suthar Suresh Kumar Angurana |
| author_sort | Siva Vyasam |
| collection | DOAJ |
| description | We report a case of acute leukoencephalopathy with restricted diffusion (ALERD) in a 2½-year-old male who presented with fever, seizures, and altered sensorium. Cerebrospinal fluid showed lymphocytic pleocytosis, whereas brain magnetic resonance imaging revealed T2 hyperintensities with restricted diffusion in cortical and subcortical regions. The patient was treated with antiseizure medications, acyclovir, methylprednisolone, and intravenous immunoglobulin. This case highlights the importance of early recognition and prompt treatment of ALERD in children, emphasizing the need for increased awareness among pediatric healthcare providers to improve patient outcomes. |
| format | Article |
| id | doaj-art-3e99da0eaba54a59bbb943dd19d3af79 |
| institution | DOAJ |
| issn | 0973-4651 2666-4054 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Current Medical Issues |
| spelling | doaj-art-3e99da0eaba54a59bbb943dd19d3af792025-08-20T02:56:40ZengWolters Kluwer Medknow PublicationsCurrent Medical Issues0973-46512666-40542025-07-0123321221410.4103/cmi.cmi_6_25Acute Leukoencephalopathy with Diffusion Restriction in a ToddlerSiva VyasamJyothi JayaramNaga Anudeep MylavarapuAnuj GuleriaSiddharth KhannaRenu SutharSuresh Kumar AnguranaWe report a case of acute leukoencephalopathy with restricted diffusion (ALERD) in a 2½-year-old male who presented with fever, seizures, and altered sensorium. Cerebrospinal fluid showed lymphocytic pleocytosis, whereas brain magnetic resonance imaging revealed T2 hyperintensities with restricted diffusion in cortical and subcortical regions. The patient was treated with antiseizure medications, acyclovir, methylprednisolone, and intravenous immunoglobulin. This case highlights the importance of early recognition and prompt treatment of ALERD in children, emphasizing the need for increased awareness among pediatric healthcare providers to improve patient outcomes.https://journals.lww.com/10.4103/cmi.cmi_6_25acute encephalitis syndromeacute leukoencephalopathy with restricted diffusionmethylprednisolonestatus epilepticus |
| spellingShingle | Siva Vyasam Jyothi Jayaram Naga Anudeep Mylavarapu Anuj Guleria Siddharth Khanna Renu Suthar Suresh Kumar Angurana Acute Leukoencephalopathy with Diffusion Restriction in a Toddler Current Medical Issues acute encephalitis syndrome acute leukoencephalopathy with restricted diffusion methylprednisolone status epilepticus |
| title | Acute Leukoencephalopathy with Diffusion Restriction in a Toddler |
| title_full | Acute Leukoencephalopathy with Diffusion Restriction in a Toddler |
| title_fullStr | Acute Leukoencephalopathy with Diffusion Restriction in a Toddler |
| title_full_unstemmed | Acute Leukoencephalopathy with Diffusion Restriction in a Toddler |
| title_short | Acute Leukoencephalopathy with Diffusion Restriction in a Toddler |
| title_sort | acute leukoencephalopathy with diffusion restriction in a toddler |
| topic | acute encephalitis syndrome acute leukoencephalopathy with restricted diffusion methylprednisolone status epilepticus |
| url | https://journals.lww.com/10.4103/cmi.cmi_6_25 |
| work_keys_str_mv | AT sivavyasam acuteleukoencephalopathywithdiffusionrestrictioninatoddler AT jyothijayaram acuteleukoencephalopathywithdiffusionrestrictioninatoddler AT nagaanudeepmylavarapu acuteleukoencephalopathywithdiffusionrestrictioninatoddler AT anujguleria acuteleukoencephalopathywithdiffusionrestrictioninatoddler AT siddharthkhanna acuteleukoencephalopathywithdiffusionrestrictioninatoddler AT renusuthar acuteleukoencephalopathywithdiffusionrestrictioninatoddler AT sureshkumarangurana acuteleukoencephalopathywithdiffusionrestrictioninatoddler |