Biofabrication, characterization and antibacterial efficacy of extracellular silver nanoparticles using novel fungal strain of Penicillium atramentosum KM

The biofabricated silver nanoparticles are extensively used in environmental, biotechnological and biomedical applications. The synthesis of SNPs has been carried out by using the filtrate extract of novel fungal strain Penicillium atramentosum KM. To undertake this study, P. atramentosum KM extract...

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Main Authors: Vikas Sarsar, Manjit K. Selwal, Krishan K. Selwal
Format: Article
Language:English
Published: Springer 2015-11-01
Series:Journal of Saudi Chemical Society
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Online Access:http://www.sciencedirect.com/science/article/pii/S1319610314000921
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author Vikas Sarsar
Manjit K. Selwal
Krishan K. Selwal
author_facet Vikas Sarsar
Manjit K. Selwal
Krishan K. Selwal
author_sort Vikas Sarsar
collection DOAJ
description The biofabricated silver nanoparticles are extensively used in environmental, biotechnological and biomedical applications. The synthesis of SNPs has been carried out by using the filtrate extract of novel fungal strain Penicillium atramentosum KM. To undertake this study, P. atramentosum KM extract was exposed to silver nitrate and the obtained SNPs were thoroughly analyzed using physicochemical characterization tools such as UV–visible spectroscopy (UV–vis), Fourier transformation infrared (FTIR), X-ray diffraction (XRD) and transmission electron microscopy (TEM). As evident from the FTIR spectra plausibly the protein components of fungal extract caused the reduction of silver nitrate. The SNPs showed a characteristic UV–visible peak at 420 nm with an average size of 5–25 nm. The XRD record exhibited the characteristic peaks of 111, 200, 220 and 311 nanoparticles signifying that these nanoparticles were crystalline in nature. Parametric optimization showed maximum absorbance of 420 nm at pH 7, 25 °C with 3 mM silver nitrate, concentration ratio of fungal extract and silver nitrate was 5:5 in 72 h. The synthesized SNPs showed antimicrobial activity against bacterial strains.
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spelling doaj-art-3e958da4172c451da7de50c6bcd601d12025-08-20T03:48:41ZengSpringerJournal of Saudi Chemical Society1319-61032015-11-0119668268810.1016/j.jscs.2014.07.001Biofabrication, characterization and antibacterial efficacy of extracellular silver nanoparticles using novel fungal strain of Penicillium atramentosum KMVikas SarsarManjit K. SelwalKrishan K. SelwalThe biofabricated silver nanoparticles are extensively used in environmental, biotechnological and biomedical applications. The synthesis of SNPs has been carried out by using the filtrate extract of novel fungal strain Penicillium atramentosum KM. To undertake this study, P. atramentosum KM extract was exposed to silver nitrate and the obtained SNPs were thoroughly analyzed using physicochemical characterization tools such as UV–visible spectroscopy (UV–vis), Fourier transformation infrared (FTIR), X-ray diffraction (XRD) and transmission electron microscopy (TEM). As evident from the FTIR spectra plausibly the protein components of fungal extract caused the reduction of silver nitrate. The SNPs showed a characteristic UV–visible peak at 420 nm with an average size of 5–25 nm. The XRD record exhibited the characteristic peaks of 111, 200, 220 and 311 nanoparticles signifying that these nanoparticles were crystalline in nature. Parametric optimization showed maximum absorbance of 420 nm at pH 7, 25 °C with 3 mM silver nitrate, concentration ratio of fungal extract and silver nitrate was 5:5 in 72 h. The synthesized SNPs showed antimicrobial activity against bacterial strains.http://www.sciencedirect.com/science/article/pii/S1319610314000921Antimicrobial activityFTIRSilver nanoparticlesTEMUV–vis spectroscopyXRD
spellingShingle Vikas Sarsar
Manjit K. Selwal
Krishan K. Selwal
Biofabrication, characterization and antibacterial efficacy of extracellular silver nanoparticles using novel fungal strain of Penicillium atramentosum KM
Journal of Saudi Chemical Society
Antimicrobial activity
FTIR
Silver nanoparticles
TEM
UV–vis spectroscopy
XRD
title Biofabrication, characterization and antibacterial efficacy of extracellular silver nanoparticles using novel fungal strain of Penicillium atramentosum KM
title_full Biofabrication, characterization and antibacterial efficacy of extracellular silver nanoparticles using novel fungal strain of Penicillium atramentosum KM
title_fullStr Biofabrication, characterization and antibacterial efficacy of extracellular silver nanoparticles using novel fungal strain of Penicillium atramentosum KM
title_full_unstemmed Biofabrication, characterization and antibacterial efficacy of extracellular silver nanoparticles using novel fungal strain of Penicillium atramentosum KM
title_short Biofabrication, characterization and antibacterial efficacy of extracellular silver nanoparticles using novel fungal strain of Penicillium atramentosum KM
title_sort biofabrication characterization and antibacterial efficacy of extracellular silver nanoparticles using novel fungal strain of penicillium atramentosum km
topic Antimicrobial activity
FTIR
Silver nanoparticles
TEM
UV–vis spectroscopy
XRD
url http://www.sciencedirect.com/science/article/pii/S1319610314000921
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AT manjitkselwal biofabricationcharacterizationandantibacterialefficacyofextracellularsilvernanoparticlesusingnovelfungalstrainofpenicilliumatramentosumkm
AT krishankselwal biofabricationcharacterizationandantibacterialefficacyofextracellularsilvernanoparticlesusingnovelfungalstrainofpenicilliumatramentosumkm